PHYTOCHEMICAL SCREENING, ANTIMICROBIAL EVALUATION AND GC-MS ANALYSIS OF CYPERUS ROTUNDUS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2019, Vol 8, Issue 9
Abstract
Cyperus rotundus L. commonly called nut grass is a highly potent traditional herbal drug used for the treatment of a number of ailments. The present study was aimed to evaluate the antimicrobial activity as well as determine the possible bioactive components of Cyperus rotundus rhizomes using GC-MS analysis. In this study, the plant rhizomes were extracted with 85% methanol and quantitative phytochemical screening was determined. Also, antimicrobial activity of the plant was estimated against fungi and bacteria (Gram positive and Gram negative) by using the agar well diffusion method. The chemical compositions of the methanol extract of Cyperus rotundus rhizomes were investigated using Gas chromatography The results exhibited that the plant has antimicrobial activity against the tested species except Proteus vulgaris. Forty four compounds were identified by GC-MS analysis; linolenic acid (21.9%) was found to be major component followed by hexadecanoic acid, 2-methyl-ester(9.1%), γ – curjunene (5.72%), oleic acid (5.45%), 1-(+)-ascorbic acid 2,6 dihexadecanoate (5.39%), larixol (3.76%), limonen-6-ol,pivalate (3.63%), longipinocarvone (3.11%), methyl stearate (3.11%), aristolone (2.84%), sclareol (2.44%), dodecanoic acid (2.29%) and platambin (2.18%). These results have shown that the plant has a significant biological effect, which can be used as an antimicrobial drug against bacteria and fungi.
Authors and Affiliations
Dr. Heba Abel-Hady
Keywords
Related Articles
- EP ID EP669115
- DOI -
- Views 112
- Downloads 0
A REVIEW ON ANTI-TUBERCULOSIS DRUGS POSSESSING VARIOUS PHARMACOLOGICAL AND BIOLOGICAL EVALUATION
Tuberculosis (TB) is an ancient disease with high incidence and mortality rates in Africa and Asian countries. This can be because of Multidrug resistant (MDR) TB, extensively drug resistant (XDR) TB and human immunodefi...
EFFECTS OF AIR-POLLUTION ON SKIN AGEING
Now a day’s air pollution becomes a great trouble in health concern for every individual. In ayurved, Acharya Charak in Charak Samhita Vimaan sthan mentioned that “Vikrit vaayu causes anaarogyam” (diseases). Polluted air...
ANTIFUNGAL ACTIVITIES OF SOME MEDICINAL PLANTS ON THE GROWTH OF CANDIDA ALBICANS
The aim of this study was to determine the in vitro effects of aqueous and ethanolic extract of four local plants: Alligator pepper (Aframomum melegueta), Ginger (Zingiber officinale), Cloves (Syzygium aromaticum) and As...
ORAL GLUCOSE TOLERANCE TEST (OGTT) WITH A COMBINATION OF COLOCASIA ESCULENTA STEMS AND EICHHORNIA CRASSIPES AERIAL PARTS
Background: In previous experimental studies, it was observed that various parts of Colocasia esculenta (L.) Schott possess antihyperglycemic potential. The objective of the present study was to determine the antihypergl...
PHARMACOKINETICS AND TISSUE RESIDUES OF MARBOFLOXACIN IN NORMAL AND EXPERIMENTALLY ESCHERICHIA COLI INFECTED BROILER CHICKEN
The pharmacokinetic parameters of marbofloxacin were studied following intravenous and oral (single & repeated) administrations in normal and experimentally Escherichia coli infected broiler chicken. Following a single i...