Plasma Protein Patterns in Pulmonary Tuberculosis Using Protein Electrophoresis
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 3
Abstract
Serum protein was analyzed by electrophoresis and photometric method in sera of adults’ patients with pulmonary tuberculosis and adults healthy individuals. Results were found to be as follows: A) The mean values of the different patterns in the patients group are as follows; total proteins (7.87g/dl, SD ± 1.18 ), albumin (3.49 g/dl, SD ± 0.80), α-1(0.63g/dl, SD ± 0.26), α-2 (1.84 g/dl, SD ± 0.564), β-1 (0.86 g/dl, SD ± 0.36), β-2 (0.70 g/dl, SD ± 0.47), and γ- globulins (0.97 g/dl, SD ± 0.43). B) The mean values of the different patterns in the healthy group are as follows; total proteins (7.290 g/dl, SD ± 0.61), albumin (4 g/dl, SD ± 0.54), α-1 (0.42 g/dl, SD ± 1.06), α-2 (1.26 g/dl, SD ± 0.46), β-1 (0.94 g/dl, SD ± 1.02), β-2 (0.57 g/dl, SD ± 0.18), and γ- globulins (0.84 g/dl, SD ± 0.48). It has been observed that there is a significant difference in total proteins, albumin, and α- 2 fractions. There are no changes in the rest of the patterns. In pulmonary tuberculosis, in spite of the lowered serum albumin, total protein level is maintained by a corresponding increase in the level of globulins resulting in the reversal of albumin/globulin ratio. Keywords: electrophoresis, pulmonary tuberculosis.
Authors and Affiliations
Omer Balla Ibrahim, Amin Mohammed, Amira Abd Alla, Sawsan Ahmed, Rayan Alhadi
Keywords
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