Platelet Rich Plasma as a Boon for Osteoarthritic Knees-A Prospective Observational Study

Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 3

Abstract

ABSTRACT Introduction: Knee pain is a leading cause of disability and the most prevalent form in the world. It is associated with tissue inflammation, physical disability and imbalanced homeostasis in cartilage. As the number of people with age greater than 35 years increases, so does the prevalence of knee pain and the need for cost effective treatment and care. A treatment strategy is needed which takes into account the underlying physiology of degenerative joint disease, but it should also consider the different age ranges and their needs in different population. Aim: To assess the clinical and functional benefits associated with the use of intra-articular Platelet Rich Plasma (PRP) in treatment of patients with knee pain of primary Osteoarthritis (OA). Materials and Methods: A prospective observational study of 50 patients visiting the outpatient department from 1st January 2013 to 31st December 2015 with Kellgren and Lawrence Grade 1 and 2 OA knees were evaluated with the Western Ontario and McMaster Universities Arthritis Index (WOMAC) before the treatment and at 1, 3 and 9 months after the PRP intra-articular treatment. Results: Statistically significant improvements in WOMAC scores were noted in all the evaluated measures in all patients. Conclusion: A minimum of two intra-articular injections of PRP is an effective treatment for mild to moderate osteoarthritis of knees.

Authors and Affiliations

Pramod Shekarappa Chinder, Bheemsingh Samorekar, Swathi Sridhar, Gururaj A Rao, Sreedhar Reddy Uyyalawada

Keywords

Related Articles

Therapy Related Acute Promyelocytic Leukaemia (APML) in a Breast Cancer Survivor: Another Tale of an Ally Turned Adversary

ABSTRACT With an increase in the use of high dose chemotherapeutic regimens, higher cure rates and longer survival periods of cancer patients, the incidence of secondary malignancies are increasing. Therapy related Myelo...

Clinicopathological Characteristics and Outcomes of Diffuse Crescentic Glomerulonephritis - A Single Center Experience from Southern India

Introduction: Diffuse Crescentic glomerulonephritis (CrGN) is characterized by rapidly progressive renal failure and has grave prognosis. There is significant regional and temporal variation in aetiology, prevalence and...

Effect of Ranolazine in Patients with Chest Pain and Normal CoronariesA Hospital Based Study

Introduction: There is an important role of coronary microcirculation in the clinical presentation and prognosis of patients who have typical chest pain despite normal epicardial coronary arteries (microvascular angina)....

Comparative Assessment of the Antibacterial Efficacy of Natural Products and Chlorhexidine Mouthwash against Streptococcus Mutans: A Systematic Review

ABSTRACT Introduction: Dental caries is still an existing challenge worldwide and continues to be the most prevalent of all oral infectious diseases. Mutans streptococci have been identified as the causative organism for...

A Rare Case of Successfully Treated Coombs Negative Immune Haemolytic Anaemia in Pregnancy

Immune haemolytic anaemia in pregnancy, although rare, but it can be life threatening. Severe anaemia with jaundice, unresponsive to blood transfusion can clinch the diagnosis of immune haemolytic anaemia. Our patient wa...

Download PDF file
  • EP ID EP513376
  • DOI 10.7860/JCDR/2018/31013.11244
  • Views 39
  • Downloads 0

How To Cite

Pramod Shekarappa Chinder, Bheemsingh Samorekar, Swathi Sridhar, Gururaj A Rao, Sreedhar Reddy Uyyalawada (2018). Platelet Rich Plasma as a Boon for Osteoarthritic Knees-A Prospective Observational Study. Journal of Clinical and Diagnostic Research, 12(3), 6-9. https://europub.co.uk/articles/-A-513376