POLYMER BIOCOMPOSITES USED IN BEDSORES TREATMENT
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2011, Vol 0, Issue
Abstract
Investigations are presented in the preparation of composite dressing material based on two biopolymers -chitosan and sodium alginate with the addition of sulfanilamide as medication designed for the healing of bedsores. The dressing was prepared in the form of film. The biopolymers used in the construction of the film make the dressing biodegradable and resorbable in the wound’s environment. Mechanical properties of the film were tested: thickness, extension strength, tenacity and elongation at maximum stress The ability of the material to match the wound was examined, too, as well as the transmission of water vapor. Sulfanilamide as bacteriostatic agent was added to the prepared composites. Mechanical and sorption properties of the composite dressings with addition of the active substance depend largely on their composition. The sorption properties were tested before and after addition of the medication .The release of the medication is intricate and proceeds according to kinetics of first order. Susceptibility of the composite materials to hydrolytic and enzymatic degradation was assessed.
Authors and Affiliations
Maria Wiśniewska-Wrona, Magdalena Kucharska, Iwona Kardas, Andrzej Bodek, Kazimiera H. Bodek
Keywords
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