POLYMER BIOCOMPOSITES USED IN BEDSORES TREATMENT
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2011, Vol 0, Issue
Abstract
Investigations are presented in the preparation of composite dressing material based on two biopolymers -chitosan and sodium alginate with the addition of sulfanilamide as medication designed for the healing of bedsores. The dressing was prepared in the form of film. The biopolymers used in the construction of the film make the dressing biodegradable and resorbable in the wound’s environment. Mechanical properties of the film were tested: thickness, extension strength, tenacity and elongation at maximum stress The ability of the material to match the wound was examined, too, as well as the transmission of water vapor. Sulfanilamide as bacteriostatic agent was added to the prepared composites. Mechanical and sorption properties of the composite dressings with addition of the active substance depend largely on their composition. The sorption properties were tested before and after addition of the medication .The release of the medication is intricate and proceeds according to kinetics of first order. Susceptibility of the composite materials to hydrolytic and enzymatic degradation was assessed.
Authors and Affiliations
Maria Wiśniewska-Wrona, Magdalena Kucharska, Iwona Kardas, Andrzej Bodek, Kazimiera H. Bodek
Keywords
Related Articles
- EP ID EP73669
- DOI -
- Views 102
- Downloads 0
MODIFICATION OF RELEASE RATE OF SALICYLIC ACID FROM CHITOSAN MEMBRANE
Due to continued interest in biodegradable polymers, chitosan is one of the most commonly used polymers in the field of control release of active substances. Currently as carriers of drugs, among tablets, or micro sphere...
THE USE OF POLYSACCHARIDES FOR ACID RED 18 ANIONIC DYE REMOVAL FROM AQUEOUS SOLUTIONS
In the paper, the adsorption of Acid Red 18 (AR18) on chitosan (CHs), sodium carboxymethyl cellulose (CMC) and agar (AGA) was researched. The adsorption capability of biosorbents was examined as a function of initial pH,...
THE INFLUENCE OF CHITOSAN FLAKE DEACETYLATION DEGREE ON ORTHOPHOSPHATE SORPTION EFFICIENCY FROM AQUEOUS SOLUTIONS
The article presents the effectiveness of orthophosphate sorption from aqueous solutions depending on the deacetylation degree of chitosan flakes. The first stage of the research was to determine the pH value at which th...
RHEOLOGICAL PROPERTIES OF CHITOSAN BLENDS WITH PARTIALLY HYDROLYZED POLYACRYLAMIDE IN DIFFERENT SOLVENTS
In the present paper, the results of rheological measurements in solutions of chitosan (Ch) with partially hydrolyzed polyacrylamide (HPAM) are presented. Aqueous acetic acid, lactic acid and aqueous acetic acid/NaCl wer...
APPLICATION OF CHITOSAN IONICALLY CROSSLINKED WITH SODIUM EDETATE FOR REACTIVE DYES REMOVAL FROM AQUEOUS SOLUTIONS
In this study, we investigated the effect of chitosan crosslinking with sodium edetate (SE) on its sorption capacity of Reactive Black 5 and Reactive Yellow 84 dyes. The first stage of the study allowed establishing cond...