Polymers in Drug Delivery Technology, Types of Polymers and Applications
Journal Title: Scholars Academic Journal of Pharmacy - Year 2016, Vol 5, Issue 7
Abstract
Abstract:Polymers play a major role in the development of drug delivery technology by release of two types of drugs like hydrophilic and hydrophobic. In a synchronized manner and constant release of formulations over extended periods. There are numerous advantages of polymers acting as an inert carrier to which a drug can be conjugated, for example the polymer improves the pharmacokinetic and pharmacodynamic properties of biopharmaceuticals through various ways, like plasma ½ life, decreases the immunogenicity, build ups the stability of biopharmaceuticals, improves the solubility of low molecular weight drugs, and has a potential of targeted drug delivery. However they have their own limitations, such as the naturals polymers are most abundant and biodegradable but are difficult to reproduce and purify. Synthetic polymers have high immunogenicity, which prevent their long term usage. Non-biodegradable polymers are needed to be sugary after they release the drug at the targeted site. The general characteristic features that makes the polymer a potential candidate for drug delivery include, safety, efficacy, hydrophilicity, absence immunogenicity biological inactivity, sufficient pharmacokinetics, and presence of functional groups for covalent conjugation of drugs, targeting moieties, or formation of copolymer. Keywords:polymer, pharmacokinetics, controlled drug delivery, target-base drug deliver, co polymer, novel drug delivery.
Authors and Affiliations
V SriVajra Priya, HareKrishna Roy, N jyothi . , N Lakshmi Prasanthi
Keywords
Related Articles
- EP ID EP377722
- DOI -
- Views 84
- Downloads 0
In-Vivo anthelmintic Activities of Ethanol Extract of Croton (Codiaeum variegatum L. Blume) Against Tapeworm Hymenolepis microstoma
As per reported in a previous study, the extract of the croton twig possesses an anthelmintic activity against the Hymenolepis spp cestode in an in Vitro model. The aim of the present study was to determine the anthelmin...
Phytochemical Screening and Fluorescence Analysis of Methanolic Flower Extracts of Punicagranatum L.
To determine various phytoconstituents present in flowers of Punic granatum. Qualitative phytochemical analysis and fluorescence analysis was done by standard methods. The Phytochemical tests were carried out on the extr...
A Pharmacognostic and pharmacological overview on Woodfordia fruticosa Kurz.
Woodfordia fruticosa is locally known as Dhawai, belonging to the Lythraceae family. Woodfordia fruticosa is an important medicinal plant of tropical and subtropical India. It has wide range of medicinal and pharmacologi...
Induction and Impact of Antibiotic Resistance on Public Health and Role of Market Stakeholder for Preventions
Abstract: The expanding resistance of microbes to normal anti-infection agents is a standout amongst the most vital and broad medical problems since current drug started. In spite of an expanding pervasiveness of antimic...
Synthesis, characterization and Evaluation for Anxiolytic activities of some Novel 4-Thiazolidinone Derivatives
The objective of the present work is to synthesis of N-[2-(4-substituted phenyl)-4-oxo-1,3-thiazoldine-3-yl]-2-(naphthalene-2-yloxy) acetamide and evaluate for anxiolytic activity. Based on this a new series of compounds...