POLYMORPHISM OF TNF-ALPHA GENE IN LOCALIZED AND GENERALIZED PYOSEPTIC DISEASES IN CHILDREN
Journal Title: Ukrainian Scientific Medical Youth Journal / Український Науково-Медичний Молодіжний Журнал - Year 2012, Vol 68, Issue 2
Abstract
In the article is shown the data on single polymorphism of a TNF-ALPHA gene as a predictor of the development of pyoseptic children diseases generalized forms. 27 children with localized and generalized pyoseptic diseases were examined. They were diagnosed with polyphormism of a promoter site of TNF-ALPHA gene in point 308 (G!A). It was established that the presence of an тwild-type of the TNF-ALPHA (308 À) gene is a factor of a risk of the development of a generalized form of the infection.
Authors and Affiliations
M. Murgina, L. Pipa
Keywords
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