Postmortem Interval Estimation Using Myoglobin Concentration in Different Glandular Tissues
Journal Title: International Journal of Forensic Science & Pathology (IJFP) - Year 2016, Vol 4, Issue 8
Abstract
Postmortem interval (PMI) estimation is very important in a suspicious death investigation. Myoglobin is a hemoprotein presents in striated muscles of living body. After death, myoglobin is exuded from muscles to blood, tissues and organs. So, the aim of this study was to estimate PMI from myoglobin concentrations in glandular tissues. This study was done on rats to detect the Postmortem concentration of myoglobin in pituitary, parotid and adrenal glands at different time intervals. There was a significant correlation between myoglobin concentration in glandular tissues and PMI. By multiple stepwise linear regression analysis, the most predictable model was the combination between pituitary, adrenal and parotid myoglobinconcentrations (R2 = 0.992). The second predictable model was the combination between adrenal and pituitary myoglobin concentrations (R2 =0.99). The last predictable model was adrenal myoglobin concentration (R2 = 0.980). It was confirmed that myoglobin concentration in glandular tissues is a helpful parameter in estimation of PMI.
Authors and Affiliations
Shereen abd-elhakim Abd-elaleem
Keywords
Related Articles
- EP ID EP200439
- DOI 10.19070/2332-287X-1600062
- Views 161
- Downloads 0
Langerhans Cell - The Destination of Migration
Langerhans cells (LCs) capture irritant substances in the skin, and then LCs migrate to the lymph nodes for presenting antigens. For investigating this, we used mites antigen labeled with PKH26 dye in atopic model NC mic...
Acridine Orange Fluroscence Study of Lung - Histopathology in Autopsy Cases of Burns
Background: The major cause of death in the burn patients includes multiple organ failure and septicemia but, sometimes the exact cause of death in many fatally burn patients is difficult to detect. Aim: The aim was to s...
A Method for the Differentiation of Single-Base and Double-Base Smokeless Powders using the Hanging Drop Technique
Bulk smokeless gunpowder is manufactured in a large variety of shapes, sizes, and textures, many different types look similar, making it challenging to differentiate between types of powders. One chemical discriminating...
Association Between the Polymorphism of the Angiotensin - Converting Enzyme Gene and Breast Cancer Risk Among the Bengalee Caste Hindu Females of West Bengal, India
Carcinoma of the breast is the most common malignancy among women all over the world. There are a number of risk factors associated with the disease. There is an inter-individual variability in breast cancer risk that at...
Medicolegal Autopsies - Interesting and Incidental Findings Research
An autopsy consists of a thorough examination of a corpse to determine the cause and manner of death and to evaluate any disease or injury. This is a retrospective study of seven years where organs of total 53 medicolega...