Potential of Indonesian Herbal Medicine, Phaleria macrocarpa (Scheff.) Boerl, for Targeting Multiple Malignancy Signaling Pathways: An Introductory Overview
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 11, Issue 2
Abstract
A wide variety of natural compounds have been recognized for targeting multiple malignancy signaling pathways and inducing apoptosis in various cancer cell lines from different origins. The chemical compositions of those substances present in plants contribute to their significant biological and medicinal value. In this review, we summarized our current findings and knowledge of bioactive compounds isolated from the Indonesian medicinal herb, Phaleria macrocarpa (Scheff.) Boerl, also known as Mahkota Dewa (MaDe) that originated from Papua province. A growing body of evidence from several countries suggests that the plant possesses potential for cancer therapy and chemoprevention. Exploring its mechanism in targeting multiple malignancy signaling pathways will provide valuable information for possible clinical applications in cancer management.
Authors and Affiliations
Ahmad Faried, Hendrikus Masang Ban Bolly, Leri Septiani, Dikdik Kurnia, Muhammad Zafrullah Arifin, Firman Fuad Wirakusumah
Keywords
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- EP ID EP349629
- DOI 10.9734/EJMP/2016/20760
- Views 108
- Downloads 0
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