Predictive Performance of Quick Sequential Organ Failure Assessment Scoring in an Argentinian Hospital
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 10
Abstract
ABSTRACT Introduction: The early identification and treatment of sepsis in emergency setting could improve patients’ survival. The Quick-SOFA score is a simple tool that could contribute to this identification. Aim: To evaluate mortality rate in Emergency Department along with predicting sepsis by Quick-SOFA. Materials and Methods: This was an observational, prospective study performed in an emergency department of an Argentine Hospital. The studied patients were ≥18 years of age, with infection or suspicion of infection. For qSOFA, 1 point was assigned for each of following: respiratory rate >21 breaths/min, systolic arterial blood pressure ≤100 mm Hg, and altered mental status. A qSOFA score of ≥2 was considered positive. To assess the performances of the qSOFA and SIRS, sensitivity and specificity was calculated. Results: A total of 157 patients were included with mean age corresponding to 62.9±19.2 years out of which 76 (48.4%) patients were women. Upon admission, 58/157 (36.9%) patients showed a positive-qSOFA, and 120/157 (76.4%) patients were SIRS positive (≥2 signs). 69/157 (46%) cases developed sepsis; 22/157(14%) patients died during their stay. The discrimination of sepsis using qSOFA was comparable with the SIRS criteria (p=0.399) and the discrimination of in-hospital mortality using qSOFA was better than SIRS criteria (p=0.0488). A qSOFA Area Under the Curve (AUC) for predicting sepsis was 0.765 (95% CI 0.69-0.84) while qSOFA AUC for predicting in-hospital mortality was 0.71, (95% CI 0.59-0.83). Conclusion: The newly introduced qSOFA provided better discrimination than SIRS for predicting in-hospital mortality whereas both scores showed comparable discrimination for predicting sepsis in Emergency Department.
Authors and Affiliations
Javier Osatnik, Bárbara Tort-Oribea, Juan Folco, Ariel Sosa, Dabiel Ivulich, María Mercedes Kleinert, Javier Eugenio Roberti
Keywords
Related Articles
- EP ID EP526802
- DOI 10.7860/JCDR/2018/37018.12150
- Views 73
- Downloads 0
De Novo Focal Segmental Glomerulosclerosis in Renal Allograft-Histological Presentation and Clinical Correlation: Single Centre Experience
Introduction: Recurrent or de novo glomerulonephritis are one of the well-known causes for renal allograft dysfunction in early and late period after renal transplantation. Focal Segmental Glomerulosclerosis (FSGS) is a...
Hyper IgE Syndrome
Letter to Editor
An In vitro Comparative Evaluation of Disinfectants on Standard and Clinical Microbial Strains on Heat Cure Resins
Introduction: Oral cavity is colonised by numerous microorganisms that form a biofilm on the acrylic resin. Hence, routine hygiene is essential to prevent oral mucosal inflammation and lesions. Knowledge of appropriate d...
Oncogenic Human Papillomavirus Genotypes and Cervical Cancer: A Focus on Multiple Infections and Patient Age
ABSTRACT Introduction: Cervical cancer is the leading cause of cancer-related deaths in the female population. Human Papillomavirus (HPV) genotypes 16 and 18 accounts for 70% of cervical cancer cases. HPV infection is as...
Rapid Identification of Vancomycin Resistant Enterococcus Faecalis Clinical Isolates using a Sugar Fermentation Method
Introduction: Vancomycin Resistant Enterococci (VRE) can be found all over the world. Thus, rapid detection of the isolates could be of high importance in the treatment or prevention of the associated disease. Aim: To me...