Pregnancy Complications - Consequence of Polycystic Ovary Syndrome or Body Mass Index?
Journal Title: Chettinad Health City Medical Journal - Year 2017, Vol 6, Issue 1
Abstract
Hyperinsulinemia and hyperandrogenemia are the hormonal changes which are linked to the pregnancy compli- cations seen in women with Polycystic Ovary Syndrome (PCOS). Aim : This study was done to determine the complications that can occur in pregnant women with polycystic ovary syndrome, and to ascertain whether the complications are related to PCOS per se or the Body Mass Index (BMI) of the women. Materials and Methods : Data was collected from case records. Study group had women with PCOS, selected according to Rotterdam criteria and control group had women with unexplained infertility, with women in both groups achieving pregnancy either spontaneously, following ovulation induction (OI) with timed intercourse or controlled ovarian hyperstimulation (COH) with Intrauterine insemination (IUI). Study design : A retrospective study. Study duration: Women who attended the clinic between January 2009 – Dec 2014, Study Setting : Department of Reproductive Medicine and Andrology, Chettinad Super Speciality Hospital, Chennai. Results : There were 110 women in the study group and 64 women in the control group. The age and BMI of women in both groups were comparable. The incidence of miscarriage, congenital anomalies, preterm delivery, operative delivery and neonatal complications were similar in both groups. Incidence of Gestational Diabetes mellitus (GDM) was significantly higher in women with PCOS (22.6%), and there was an upward trend with increasing BMI. There was also an increased incidence of Large for gestational age babies in women with PCOS, but there was no statistical significance. Conclusion : Unlike previous publications, our study revealed no significant increase in pregnancy and neonatal complications in women with PCOS, except for Gestational diabetes, the incidence of which was related to BMI. Therefore, we suggest that PCOS and the pregnancy complications are a consequence of increasing BMI, and that PCOS may not be incriminated as the independent cause for these complications.
Authors and Affiliations
Puvithra T, Radha P, Pandiyan N
Keywords
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