Preliminary Phytochemical and Antifungal Screening of Crude Extracts of the Bacpoa Monnieri
Journal Title: Universal Journal of Environmental Research and Technology - Year 2012, Vol 2, Issue 4
Abstract
The antifungal activity of the crude extract of the leaves and whole plant of Bacopa monnieri in total of eight solvents (or their mixtures) were screened against three main fungal pathogens responsible for the skin infections. Zone of Inhibition as well as the minimum inhibitory concentration was recorded for the most potent extract. Methanol extract was found to be the most potent extract for all the pathogens under study The major zone of inhibition was recorded for the methanol extract of whole plant against A. niger as well as M.furfur 16mm and 15mm for C. albicans with the Minimum Inhibitory Concentration (MIC) ranging from 300mg/ml and 400mg/ml for C. albicans and that for A. niger and M. furfur was recorded as 200mg/ml respectively. The GC MS analysis confirms the presence of the various phytochemicals contributing for the antifungal activity. The antifungal activity of Bacopa monnieri found to be promising against fungal pathogens also reveals the potential usefulness of the B. monnerii plant in the treatment of skin infections.
Authors and Affiliations
Meghna Udgire and G. R. Pathade
Keywords
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