PRELIMINARY PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITY OF Gymnema sylvestre: A MEDICINAL PLANT
Journal Title: Indian Journal of Scientific Research - Year 2018, Vol 8, Issue 2
Abstract
The present study was carried out to evaluate the phytochemical and antimicrobial activity of Gymnema sylvestre against ten microbial strains causing oral infections. The qualitative phytochemical analyses were carried out following the Indian pharmacopoeia and the methods. The MIC values of the plant extracts were determined against the selected test organisms using the methods as described by National Committee for Chemical Laboratory Standard and the in vitro antimicrobial activity was determined by using the agar disc diffusion method. The phytochemical analysis carried out revealed the presence of alkaloids, phenolic compounds, flavonoids, glycosides, tannins and tri terpenoids in this medicinal plant. The antimicrobial activity of five different extracts of medicinal plants were evaluated using well diffusion method against Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Salmonella typhi, Chromobacterium violaceum, Burkolderia mallei and Candida albicans respectively. The chloroform extracts of this plant shown best antimicrobial activity against selected microbes. The results provide justification for the use of the medicinal plants to treat various oral infection
Authors and Affiliations
P. BOOMIBALAGAN
Keywords
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