Prescribing Pattern of Medication in Type 2 Diabetes Mellitus with Metabolic Syndrome
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 8
Abstract
Introduction: Metabolic syndrome (MS) or X syndrome refers to simultaneous occurrence of cardiovascular risk factors such as abdominal obesity, high blood pressure and abnormal carbohydrate and lipid metabolism (hypertriglyceridemia, elevated blood glucose) and decrease in high density lipoprotein (HDL) level. Type 2 diabetes mellitus with metabolic syndrome is a multifaceted disease and needs multiple drug therapy. The present study was aimed to assess the prescribing pattern of medication among diabetic patients with metabolic syndrome and to find the associated socio-demographic factors. Material and Methods: It was a hospital based observational study. The prescriptions of 102 patients of type 2 diabetes mellitus with metabolic syndrome were collected and analyzed to evaluate the sociodemographic data and prescribing pattern of medication. Results: In antidiabetic therapy, 70.6% of patients were on combination therapy while 29.4%patients were on monotherapy. The most common prescribed anti-diabetic group, either as monotherapy or as combination therapy was biguanides(86.27%). In anti-hypertensive therapy 60.72% of patients were on combination therapy while 39.28% patients were on monotherapy. The most common prescribed antihypertensive group either as monotherapy or combination therapy was angiotensin receptor antagonists (69.04%). The most commonly prescribed hypolipidemic was statins (78.84%) while other drugs constituted only 21.15%. Conclusion: there was increase in average number of drugs per prescription (8.62) but also very less number of drugs prescribed by generic names (22%). Multiple drug therapy was used to alleviate the pleiotropic effects of this metabolic disorder. Physician should prescribe more drugs by generic name and from essential drug list and more stress should be given on lifestyle modification than polypharmacy.
Authors and Affiliations
Anusha Vohra
Keywords
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