Prescription pattern and adverse drug reaction profile of drugs prescribed with focus on NSAIDs for orthopedic indications at a tertiary care hospital
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2016, Vol 3, Issue 4
Abstract
Introduction: The Non-steroidal Anti-inflammatory Drugs (NSAIDs) constitute the largest group of drugs used worldwide for indications like rheumatoid arthritis, osteoarthritis, low back pain etc. Periodic evaluation of drug utilization patterns enable suitable modifications in prescription of drugs to increase the therapeutic benefit and decrease adverse effects. Objective: To analyze the prescription patterns and adverse drug reaction profile of NSAIDs prescribed in orthopedic outpatient department of Tertiary Care Hospital. Study design: observational, cross-sectional study. Results: 360 patients enrolled. Average number of drugs per prescription was 3.83. Total 1382 drugs were prescribed, out of which 418 were NSAIDs (30.24%). Ibuprofen was most commonly prescribed agent (62.79%), followed by Diclofenac (40.66%). Ibuprofen was found to be the commonest drug associated with ADRs. Conclusion: Ibuprofen was most commonly prescribed NSAID and also responsible for majority ADR. There was higher prevalence of irrational prescribing, polypharmacy and under reporting of ADR.
Authors and Affiliations
V. M. Motgahre, C. S. Bajait, A. Turankar, S. A. Pimpalkhute, M. Dholpure
Keywords
Related Articles
- EP ID EP240752
- DOI -
- Views 92
- Downloads 0
A cross sectional study on the practise of self-medication among 2nd year medical and dental students
Introduction: Most of the common health ailments are treated by general population themselves without medical supervision, which is termed as self-medication. There are potential risks of self-medications like adverse dr...
Study of serum glucose and cholesterol level in schizophrenic patient’s before and after treatment of olanzapine, risperidone and haloperidol
Objectives To evaluate the potential association between antipsychotics Olanzapine Risperidone and Haloperidol serum glucose level and serum cholesterol level in schizophrenic patientsIntroduction Schizophrenia is quite...
Nootropic Effect of Berberine in Colchicines Induced Experimental Alzheimer’s Disease Model: Effect on Cholinergic Neurotransmission
Background & Objectives: Colchicine administration by ICV is well known model which shows sporadic dementia of the Alzheimer type in humans, causing cognitive impairment and oxidative damage. Berberine (BBR) is a natural...
Analgesic activity of lagenaria siceraria root extract by tail flick method in albino mice
Introduction Analgesics relieve pain which otherwise can cause distress and suffering But analgesics like NSAIDs and opioids can cause side effects like gastric irritation tolerance and dependence Hence it is essential t...
Perception and practices of self medication of antibiotics among undergraduate students of a medical college
Background: the study was conducted to analyze the perceptions regarding self medication of antibiotics among medical students and to determine the practice of antibiotic self-medication among medical students. Methods:...