Prescription pattern and rational drug use in cases of enteric fever in a tertiary care hospital
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2018, Vol 7, Issue 3
Abstract
Introduction Irrational use of medication is one of the main causes of resistance. It can be prevented by giving right drug to right patients. Hence the present study was conducted to evaluate the prescribing pattern and rational drug use in cases of enteric fever. Aim To study of prescription pattern and rational drug use in cases of enteric fever in a tertiary care hospital. Methods A cross sectional study was carried out by evaluating prescription of 161 subjects who had definite diagnosis of enteric fever in Department of Pharmacology in collaboration with Department of General Medicine at Government Medical College, Kannauj from May 2018 to July 2018. The data was analyzed by using SPSS software and results were expressed as percentage. Results In this study among 161 patients of enteric fever, 56.52% were males and 43.47% were females. There were two subset of age groups in which enteric fever is most common i.e. 58.3% in age group between 21 to 40 years followed by 27.9% in age group between 1 to 20 years. Most commonly prescribed antimicrobial agents were IIIrd generation Cephalosporin’s (70.1%) followed by 1st Generation Fluoroquinolones (51.5%). Some patients also received other groups of antibiotics like Macrolides (16.1%), Metronidazole (3.7%) and Penicillins (0.6%). All the medications were prescribed using their generic names and in small letters of English. They were prescribed oral medications (86.95%) and were duly signed by the physicians but none of them followed up. 93.1% received Paracetamol as antipyretic and 2.4% of the patients received Metaclopramide as antiemetic. Conclusions The present study provided prescribing pattern in outdoor patients of tertiary hospital which highlighted the current drawbacks like polytherapy, not abiding with antibiotic policy and principles of pharmacoeconomics in prescribing antibiotics to patients of enteric fever. There was less possibility of doing sensitivity test and prescribing them single drug therapy in tertiary care hospital because most of the critical patients are referred from other centres.
Authors and Affiliations
Dr. Virendra Kushwaha
Keywords
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