PRESCRIPTION PATTERN OF CARDIOVASCULAR AND/OR ANTIDIABETIC DRUGS IN ABUJA DISTRICT HOSPITALS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 9
Abstract
Objective: The study aimed to describe the prescription pattern of cardiovascular and/or anti-diabetic drugs and adherence to the World Health Organization (WHO) prescribing indicators in Abuja District Hospitals. Methods: This descriptive retrospective study was carried out in Asokoro and Maitama District Hospitals Abuja. One thousand and nine prescriptions that contained a cardiovascular drug (CVD) and/or anti-diabetic drug issued between June 2017 and May 2018 from the Medical Outpatient Department were analyzed. Data were collected from the pharmacy electronic database, prescription pattern and adherence to WHO prescribing indicators were assessed. The analysis was done using descriptive statistics. Results were presented as percentages, means, and standard deviations. Results: The frequency of treatment was higher among women (58.8%) and the age group of 41–60 (54.8%). The average number of drugs prescribed was 3.3±1.6: the percentage of drugs prescribed in generic was (64%) and (78.8%) were from the Essential Drug List (EDL). Calcium Channel Blockers (CCB, 71.7%) and Biguanides (B, 92.4%) were the most prescribed CVD and anti-diabetic drug. The majority of the CVD (74.5%) and diabetes (63.6%) patients were on combination therapy. The most frequent CVD combination was CCB plus Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers (29.7%). Compared to men, the proportion of females taking one or more CVD (61.3%) or antidiabetic (56.4%) was higher. Conclusion: The prescribing indicators are not optimal in Abuja district hospitals. Women received more treatment for cardiovascular and diabetes diseases than men while the age range of 41-60 was more treated than other age groups.
Authors and Affiliations
NKEIRUKA GRACE OSUAFOR, CHINWE VERONICA UKWE, MATTEW JEGBEFUME OKONTA
RP-HPLC METHOD FOR ESTIMATION OF TIAPRIDE RELATED SUBSTANCE IN TABLET FORMULATION
Objective: To develop a simple, precise, accurate related substance, reverse phase high-performance liquid chomatographic (RP-HPLC) method for the quantitative estimation of impurities which are present in dosage form of...
SPECTROSCOPIC STUDIES ON POUZOLZIA WIGHTII BENN
Objective: The present study was aimed to reveal the spectroscopic profile (UV-Vis and FT-IR) of Pouzolzia wightii Benn. Methods: To detect the UV-Vis spectroscopic profile of P. wightii crude extracts were examined unde...
AMELIORATIVE EFFECTS OF ARTEMISIA JUDAICA L. EXTRACT AGAINST ALLOXAN-INDUCED BIOCHEMICAL ALTERATIONS IN MALE WISTAR RATS
Objective: The current study aims to evaluate the potential of crude leaf extract of Artemisia judaica L. (AJE) in reducing the biochemical abnormalities accompanied to alloxan-induced diabetes in male Wistar rats.Method...
ANTIOXIDANT THERAPEUTIC ACTIONS OF MEDICINAL PHYTOCHEMICALS, SILYMARIN AND SILIBININ, ON STREPTOZOTOCIN DIABETIC RATS: FIRST NOVEL COMPARATIVE ASSESSMENT OF STRUCTURAL RECOVERIES OF HISTOLOGICAL AND ULTRASTRUCTURAL CHANGES ON ISLETS OF LANGERHANS, Î’-CELLS, MITOCHONDRIA AND NUCLEUS
Objective: We studied correlation between antioxidant properties of Silymarin and Silibinin and the restoration and recovery of normal structure of islets of Langerhans β-cells and mitochondria in Streptozotocin-diabeti...
APOPTOSIS-INDUCING POTENTIAL OF LAWSONIA ALBA LAM. LEAVES ON HEPATOCELLULAR CARCINOMA (HEP-G2) CELLS ALONG WITH ITS ANTI-OXIDANT PROPERTY
Objective: The current study investigated the anti-cancer potential of methanolic and ethyl acetate fraction of Lawsonia alba L. (Lythraceae) leaves extract on Hep-G2 and RAW 264.7 cells along with in vitro anti-oxidant...