Prevalence and associated factors of congenital anomalies in a tertiary care centre in Tamilnadu
Journal Title: Obs Gyne Review: Journal of Obstetric and Gynecology - Year 2016, Vol 2, Issue 4
Abstract
Background: A birth defect or congenital anomaly is an abnormality of structure, function or body metabolism that is present at birth and results in physical or mental disability. Evaluation and management of newborns with one or more malformations present a significant challenge to the healthcare providers and families. Despite major advances in understanding the etiology and pathogenesis, malformations remain a leading cause of infant mortality. This study brings about the prevalence of congenital anomalies among antenatal patients delivering beyond the period of viability, 22 weeks in a tertiary care centre in Tamilnadu and also the pattern of anomalies, along with the associated factors. Materials and Methods: A cross sectional study with nested case control design was conducted in a tertiary care centre in Taminadu for one year from July 2015 to June 2016. Those fetuses induced in second trimester following detection by ultrasound and those babies detected to have congenital anomalies by postnatal examination were included in the study. Data of 191 cases and 191 controls were collected by interviewing the mothers and reviewing the existing patient records. Relevant antenatal, natal, postnatal and past illnesses were recorded in a proforma and analysed. Results: In the study period, 191 babies out of 9877 were anomalous with a prevalence of 1.93%. Anomalies of the central nervous system were the commonest (35.6%). The ultrasound detection rate was 67.01%. Maternal age >25 years was seen in 55%. About 15.7% of the mothers had consanguineous marriage. The distribution among primigravida and multipara are almost similar.16.2% of cases had a history of infertility in the mother. 8.4% of the cases had a family history. About 4.7% cases had a history of exposure to antiepileptic drugs. Maternal diabetes mellitus and epilepsy contributed 32.5% and 4.5% of cases respectively. Intrauterine growth restriction and amniotic fluid abnormalities were commonly associated. Conclusion: The study helps to know the pattern of congenital anomalies and the relationship of various gestational and familial factors and the importance of ultrasound in diagnosing anomalies. Surveillance of anomalies should be a must and all maternity hospitals should have their own anomaly register. Parents of any surviving anomalous child should receive emotional support and reassurance.
Authors and Affiliations
Prema N, Sudhakaran R, Divya B. V, Meerabai V, Maharani Maharani
Keywords
Related Articles
- EP ID EP228331
- DOI 10.17511
- Views 241
- Downloads 0
A Prospective study of etiology and outcome of Preterm Labour in a Rural Medical College
Introduction: Preterm birth is a major problem in developing countries contributing significantly to perinatal mortality. Preventing preterm labor is still a great challenge in modern obstetrics .Every year an estimated...
Heme iron polypeptide in treatment of anemia inpregnancy
Introduction: Treatment of iron deficiency anemia with non-heme iron salts still remains a challenge. The negative influence of various dietary elements and medications slows the absorption of iron from iron salts which...
A study of efficacy of oral probiotics in management of cases with symptomatic white discharge per vagina in a tertiary care hospital
Background: Urogenital infections are the most common gynecological condition constituting about 25% of outpatients. Because of higher recurrence rates and resistance to standard antimicrobials now a days the use of prob...
Prevalence and associated factors of congenital anomalies in a tertiary care centre in Tamilnadu
Background: A birth defect or congenital anomaly is an abnormality of structure, function or body metabolism that is present at birth and results in physical or mental disability. Evaluation and management of newborns wi...
Knowledge, attitude and practice towards exclusive breast feeding among lactating mothers in a South Indian Hospital
Background: Exclusive breast feeding (EBF) isconsidered when the infant does not receive any additional food or nutriment other than breast milk. Aims and Objectives: The object of the study was to assess knowledge, atti...