Prevalence and Characterization of Multi-drug Resistant Uropathogens from Children with Urinary Tract Infections in Children Emergency Unit of Federal Teaching Hospital, Abakaliki (FETHA), Nigeria
Journal Title: International Journal of Medical and Health Sciences - Year 2016, Vol 5, Issue 4
Abstract
Objective: This study was designed to determine the prevalence of common etiological agents causing urinary tract infections in children emergency unit of FETHA and their susceptibility to antibiotics. Materials and methods: Eighty urine samples from both children’s outpatient clinic and emergency wards of FETHA were collected using sterile universal containers. The collected samples were characterized using standard microbiology techniques. Isolated bacterial pathogens were subjected to antibiotic susceptibility test using the disc diffusion method. Results: Results showed that 74 bacterial isolates were obtained from the 80 urine samples collected. Thirty (37.5 %) isolates were E. coli, 12 (15.0 %) were Pseudomonas aeruginosa, 11 (13.75 %) were Proteus spp, 10 (12.5 %) were Staphylococcus aureus, 10 (12.5 %) were Klebsiella spp while 1(1.25 %) was Enterococcus feacalis. Susceptibility test results using some selected antibiotics against isolated bacterial pathogens showed that Imipenem was the least resisted antibiotic. Klebsiella spp exhibited the highest antibiotic resistance frequency as it was 100 % resistant to 9 out of 18 antibiotics tested. E. coli showed the highest multiple antibiotic resistance index (MARI) with a value of 24.45 while S. aureus, Proteus spp, Klebsiella spp and P. aeruginosa had MARI values of 6.97, 9.51, 8.90 and 9.03 respectively. Conclusion: This study showed that there is a high prevalence of multi-drug resistant uropathogens especially E. coli, among children with urinary tract infections in FETHA and the antibiotic sensitivity results showed that imipenem was the most active antibiotic against all the isolated pathogens.
Authors and Affiliations
Iroha I. R. , Ukwuani, E. O, Moses I. B, Ajah M. I, Iroha C. S, Ajah L. O
Keywords
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