Prevalence of adverse effects and efficacy of anticoagulant therapy with Dabigatranversus Warfarin in patients with non-valvular atrial fibrillation in the cardiology
Journal Title: Más Vita - Year 2022, Vol 4, Issue 4
Abstract
Introduction: Atrial fibrillation (AF) is the most frequent cardiac arrhythmia, affecting approximately 2% of the general population and its prevalence increases with age and the presence of risk factors; In addition, it can be associated with different comorbidities such as: AHT, DM, HF, AMI, among others. Objective:To determine the prevalence of adverse effects and efficacy of anticoagulant therapy with Dabigatran versus Warfarin in patients with non-valvular atrial fibrillation at the HTMC, from January 2014 to January 2018. Materials and methods: It is a retrospective study. ,analytical and descriptive; the universe was made up of 500 HTMC patients with a diagnosis of atrial fibrillation. The data collection instrument was through the IESS AS400 system, in which the information was collected from the patients' medical records and stored in Microsoft Excel. A sample was obtained, according to the inclusion criteria, giving a total of 209 patients, divided into two groups, the first of 106 patients medicated with Warfarin and the second of 103 patients who were medicated with Dabigatran. Results:The results of the assessment of thromboembolic and hemorrhagic risk were obtained, based on the CHADS2VASC and HAS BLED scales, respectively. The patients presented the samecomorbidities, there was no statistically significant difference between the different age and gender groups, neither for smoking and obesity; on the contrary, if there was a statistically significant difference for alcoholism, there is probably greater exposure to this cardiovascular risk factor in one of the groups; for heart failure, this would indicate a greater presence of heart failure in one of the groups.Conclusion:It was concluded that both groups had the same probability of presenting bleeding events through the HAS BLED score; however, the statistically significant P values for the different types of bleeding show that there is a higher prevalence of bleeding in one group than in another. It was determined that the patients medicated with Warfarin had a higher prevalence of bleeding during the 4 years of the study, unlike the group of patients medicated with Dabigatran
Authors and Affiliations
Luis Armando Rosado Vargas, André José Díaz Cabezas, Arianna Marina Navarrete Ponce, Fabio Alexander Macías Silva
Keywords
Related Articles
- EP ID EP711827
- DOI https://doi.org/10.47606/ACVEN/MV0170
- Views 56
- Downloads 0
Compliance with standards and indicators of humanized labor and birth in the type C healthcenter Velasco Ibarra, Machala Ecuador
Childbirth is an extraordinary event in a woman's life, given precisely because it is the culmination of human pregnancy and at the same time the beginning of a new life, which is why special interest is attrib...
Validation of an instrument to measure risk factors associated with quality of medical care in older adults
the risk factors associated with the quality of medical care constitute an instrument to establish the perception that users of the services have in the health systems, since it allows to explore the...
Level of satisfaction and job performance of the nursing staff
Introduction:Job satisfaction reflects the affections and emotions of the employee towards his work, allows understanding the different variables related to the efficiency of the organization, organizational com...
Validation of the instrument for the evaluation of the teaching role of external consul-tation nursing professionals
the nursing educational role is convenient to understand and in-terpret the nursing professionals and pa-tients perception about their educational experience. Education is an essential componen...
Nursing diagnosis of the emotional state in patients with chronic renal insufficiency during their treatment
Chronic renal failure (CRF) causes sudden changes in the individual'slife, such as the development of emotional disorders that can lead to anxiety, depression and stress; affecting your emotional state. Obj...