Prevalence of anti-HDV and HDAg in patients with chronic hepatitis B
Journal Title: Dicle Tıp Dergisi - Year 2013, Vol 40, Issue 1
Abstract
Objective: In this study, it is aimed to evaluate the correlation of the test results of anti-HDV and HDAg in patients with chronic HBV infection and to collect data concerning HDV epidemiology. Materials and methods: Anti-HDV and HDAg test results and demographic data of the patients with chronic HBV infection by gastroenterology and infectious diseases in Agri State Hospital between January 2009-May 2012 were analyzed retrospectively. HBsAg and Anti-HBc IgM tests were performed with macroelisa, anti-HDV and HDAg were tested with microelisa. Results: A total of 787 patients constituting 315(40.0%) females and 472(60.0%) males were included in the study. All the patients were HBsAg positive and Anti-HBc IgM negative. Of these patients, 55(7.0%) cases were only anti-HDV positive; 19(2.4%) were only HDAg positive and two cases were both anti-HDV and HDAg positive. A total of 76(9.7%) patients had positive findings of HDV infection. The mean age of HDV-positive patients was 42.1±15.2 (11-77 years); of these 36(47.4) were female and 40(52.6) were male. Conclusion: In patients with chronic viral hepatitis, HDV infection still remains significant. In our study HDV infection rate was detected as 9.7%. Although this rate is lower than the earlier reports of the same region, it is above the national average. Key words: HDV, HDAg, delta antigen, anti-HDV, chronic hepatitis B, pain
Authors and Affiliations
Mustafa Doğan, Hayati Güneş, Rafet Mete, Tekin Taş, Fırat Mengeloğlu, Abdulkadir Küçükbayrak
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