Prevalence of dry eye disease in patients on anti-depressants
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2017, Vol 3, Issue 4
Abstract
ntroduction: Dry eye is a complex multifactorial disease which forms a major proportion of ophthalmology out patients. Most of the patients are on chronic medications including psychiatric drugs. So prevalence of dry eye was studied in psychiatric patients on antidepressants. Methods: A cross sectional comparative study was conducted among 22 patients / 21 controls in a tertiary eye care hospital in Northern Kerala for a period of 1 year by assessing Ocular surface disease index score/Tear film break up time/ Schirmer test .Association of age gender, smoking, alcoholism, with dry eye disease was also studied. Results: Study showed a statistically significant correlation between antidepressant medications and dry eye with a P value of 0.012. Tricyclic anti-depressants contributed the majority for dry eye followed by selective serotonin re-uptake inhibitors and serotonin norepinephrine reuptake inhibitors. Females, old age and smoking showed high prevalence. Schirmer test was found to be 100% sensitive and specific and TBUT; 35% sensitive and 100% specific. Conclusion: Prevalence of dry eye disease is 50 % in patients on antidepressants compared to 14.2 % in control group. Schirmer test can be effectively used in patients for early detection of dry eye disease. The drugs with least side effects can be selected and treatment modified accordingly.
Authors and Affiliations
Arun Kumar A, Irshad E, Jithu V P
Keywords
Related Articles
- EP ID EP302021
- DOI 10.18231/2395-1451.2017.0111
- Views 76
- Downloads 0
The association of age-related cataract and serum Vitamin C
Purpose: To study the association of age-related cataract with serum vitamin C levels in patients presenting to a University hospital in South India. Materials and Methods: All patients above the age of 50 years, willing...
Barriers to the acceptance of cataract surgery in a hospital based population: A descriptive study
Introduction Cataract is a leading cause of blindness in low and middle income countries like India Despite free cataract services available in most government institution as part of national health program to curb blind...
To study the comparison of efficacy and side effect profile of bimatoprost 0.03% versus fixed combination timolol 0.5% and dorzolamide 2% in patients with primary open angle glaucoma or ocular hypertension
Aims: To study IOP lowering efficacy and side effect profile of bimatoprost 0.03% versus fixed combination timolol 0.5% and dorzolamide 2%. Settings and Design: Prospective, open, randomized, parallel group, comparative...
The intraocular pressure changes following intravitreal bevacizumab injections in an Indian population
Aimnbsp To assess the changes in Intraocular pressure IOP after intravitreal bevacizumab therapyDesign Prospective Observational Tertiary care hospital based studyParticipants 95 patients receiving intravitreal bevacizum...
The effect of fluticasone furoate nasal spray on the intraocular pressure in patients of allergic rhinitis: A cross sectional study from eastern India
Background Rhinoconjunctivitis is a common health problem that plagues the lives of children and adolescents alike with a significant impairment of the quality of lifePurpose Aim of this study was to investigate the effe...