Prevalence of dry eye disease in patients on anti-depressants
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2017, Vol 3, Issue 4
Abstract
ntroduction: Dry eye is a complex multifactorial disease which forms a major proportion of ophthalmology out patients. Most of the patients are on chronic medications including psychiatric drugs. So prevalence of dry eye was studied in psychiatric patients on antidepressants. Methods: A cross sectional comparative study was conducted among 22 patients / 21 controls in a tertiary eye care hospital in Northern Kerala for a period of 1 year by assessing Ocular surface disease index score/Tear film break up time/ Schirmer test .Association of age gender, smoking, alcoholism, with dry eye disease was also studied. Results: Study showed a statistically significant correlation between antidepressant medications and dry eye with a P value of 0.012. Tricyclic anti-depressants contributed the majority for dry eye followed by selective serotonin re-uptake inhibitors and serotonin norepinephrine reuptake inhibitors. Females, old age and smoking showed high prevalence. Schirmer test was found to be 100% sensitive and specific and TBUT; 35% sensitive and 100% specific. Conclusion: Prevalence of dry eye disease is 50 % in patients on antidepressants compared to 14.2 % in control group. Schirmer test can be effectively used in patients for early detection of dry eye disease. The drugs with least side effects can be selected and treatment modified accordingly.
Authors and Affiliations
Arun Kumar A, Irshad E, Jithu V P
Keywords
Related Articles
- EP ID EP302021
- DOI 10.18231/2395-1451.2017.0111
- Views 84
- Downloads 0
A comparative study on the intraocular pressure among diabetic and non-diabetic patients
Background: Diabetes mellitus is one of the major health issues affecting people across nations. The complications of diabetes mellitus affects vital organs of human body, among which eyes are more susceptible to diabeti...
A study of incidence of posterior capsular opacification after cataract surgery with square edge PMMA intra ocular lens
Introduction: PCO usually leads to a decrease in visual acuity (VA), glare disability and a loss of contrast sensitivity. It has been reported earlier that sharp edge intraocular lens optics are better than rounded edge...
Pterygium excision with conjunctival autograft with autologous blood
Aim Current study focuses to analyse the advantage of the technique which uses the autologous blood for sutureless securing the conjunctival autograft post pterygium excisionMaterials and Methods This is noninvasive stud...
A four year retrospective & prospective study of ophthalmia neonatorum
Introduction: Ophthalmia neonatorum is one of the most common infections occurring in the first month of life. 1 Neonatal ocular infections have been largely associated with various poor perinatal outcomes. The purpose o...
Comparison of post operative astigmatism from superiotemporal vs temporal incision in small incision cataract surgery
Introduction: Cataract surgery has become one of the most common and successful procedures in ophthalmology. In addition to improving visual acuity (VA), one of the goals of modern cataract surgery is to reduce pre-exist...