Role of cyclosporin 0.1% in perennial vernal keratoconjunctivitis
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2016, Vol 2, Issue 3
Abstract
Introduction: To evaluate the efficacy of topical cyclosporin A 0.1% eye drops in management of moderate to severe perennial vernal keratoconjunctivitis. Methods: Fourteen patients with moderate to severe perennial vernal keratoconjunctivitis, who were dependent on steroid eye drops for control of disease, were administered 0.1% cyclosporin A eye drops twice a day. Signs, symptoms and steroid score were calculated at start of study, and then at two monthly interval. Results: Ten males and four females, between age of 3 – 17 years were enrolled in this study. Treatment with cyclosporin A 0.1% eye drops decreased the symptom, sign and steroid score at 12 months (p<0.0001, paired t test). Steroid sparing effect was seen in five patients at the end of study period. Conclusions: Topical cyclosporin A 0.1% eye drops can be used as a steroid sparing agent in the management of perennial vernal keratoconjunctivitis.
Authors and Affiliations
Kshama Dwivedi, Arun Kumar Singh, Vanlalhruaii, Hauhner, Mimansaa Agasti
Keywords
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