PREVALENCE OF EXTENDED SPECTRUM Β-LACTAMASE (ESBL) PRODUCING ESCHERICHIA COLI AND KLEBSIELLA ISOLATED FROM VARIOUS IN PATIENT DEPARTMENT SAMPLES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
The present study was focused to isolate ESBL (Extended Spectrum Beta Lactamase) producing Escherichia coli and Klebseilla sp. from the IPD (In Patient Department) and to determine the resistant profile of ESBL producers . The tests were carried out with the help of Double Disk Approximation test and Vitek ESBL test. About 70.4% of the E.coli isolates showed the ESBL positive while about 86.1% of the Klebsiella sp. showed positive result. The antibiotics against which the bacteria’s showed the maximum resistant are Penicillin, Fluoroquinolones, Cephalosporins and Monobactum, which was 100%. The least resistant was shown against Lepopeptides. Knowledge of resistance pattern of bacterial strains in geographical areas will help to guide the appropriate and judicious antibiotic use. While comparing the result of this study with the previous studies it was concluded that the rates of ESBL positive strain vary greatly worldwide and within geographic areas and are rapidly changing overtime.
Authors and Affiliations
Rubin Dasgupta , Rajendra Sapkota
Keywords
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