PREVALENCE OF FUNGI AS OPPORTUNISTIC PATHOGENS IN ACTIVE AND POST TREATED PULMONARY TUBERCULOSIS CASES -A COMPARATIVE STUDY
Journal Title: INTERNATIONAL JOURNAL OF ADVANCED MEDICINE - Year 2018, Vol 2, Issue 6
Abstract
BACKGROUND :Tuberculosis is one of the leading causes of death all over the world. The course of infection and treatment makes the patient vulnerable to opportunistic fungal infections, which is mostly misdiagnosed. MATERIALS AND METHODS: This was a one year Cross-sectional study. In this study patients who were clinically diagnosed of Pulmonary Tuberculosis kept under Group 1 while post treated cases of pulmonary tuberculosis having respiratory symptoms were in group 2. Total 50 sputum samples were observed in each group. All the samples were subjected to KOH mount, culture and identication according to standard diagnostic criteria. These criteria included morphological and cultural characteristics, Germ tube experiment and tests for carbohydrate assimilation and fermentation. The molds isolated were subjected to LPCB mount and reported according to their distinct morphology. RESULTS: A total of 100 samples were screened(50 Active and 50 Post-treated pulmonary tuberculosis (PTB) cases), in which 55% opportunistic fungal pathogens were detected. The prevalence of opportunistic fungal infection was 58% amongst the active PTB cases and 52% in post-treated cases of pulmonary TB. Candida species (40%) were the most common isolates in active PTB cases and in post treated PTB cases Aspergillus spp.(34%) species was more common. CONCLUSION: The coexistence of fungi with tubercle bacilli complicates a patient's condition by adding more damaging and fatal dimensions to it.
Authors and Affiliations
Mohammad Aadam Bin Najeeb, Dr. Mahantesh B. Nagamoti
Keywords
Related Articles
- EP ID EP631529
- DOI -
- Views 41
- Downloads 0
EVALUATION OF DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING AGAINST CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING IN DIAGNOSIS OF SPINAL TUBERCULOSIS.
Background: Tuberculosis is a very important health issue in the developing countries. The spinal tuberculosis is characterised by intervertebral disc involvement, pre/paravertebral and epidural abscess formation, skip l...
EFFECT OF INTRAVENOUS FLUID SUPPLEMENTATION IN HEALTHY TERM NEONATES WITH NON-HEMOLYTIC HYPERBILIRUBINEMIA
Objective: The objective of this study was to evaluate the effect of intravenous uid supplementation in healthy term neonates with non-hemolytic hyperbilirubinemia receiving phototherapy. Study Design: Randomized contro...
EPIDEMIOLOGY OF EMERGENCY PEDIATRIC HOSPITALIZATIONS AT A TERTIARY CARE CENTRE IN NORTH INDIA
Background: Epidemiological data assessment is an important tool for measuring the burden of disease in population. Demographic prole, geographical distribution and outcome of the disease can vary in pediatric emergenci...
PREVALENCE OF NON COMPLIANCE WITH ANTI TB TREATMENT AND ITS CONTRIBUTING FACTORS AMONG TUBERCULOSIS PATIENTS.
INTRODUCTION: Tuberculosis is a worldwide, chronic communicable bacterial disease. One third of the world's population is infected with TB. The main objective of study was to assess the prevalence of non compliance and t...
POST-THERAPY OUTCOME AND ECHOCARDIOGRAPHIC ANALYSIS AT THREE WEEKS OF ELDERLY PATIENTS WITH ACUTE MYOCARDIAL INFARCTION FOLLOWING THROMBOLYSIS THERAPY
Introduction: Once severe ischemia has lasted for about 20 minutes, myocardial necrosis ensues, affecting the subendocardium rst and then proceeding in a time dependent wave front to reach epicardium about 4 to 6 hours...