PREVALENCE OF H. PYLORI IN DUODENAL ULCER PERFORATION

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PREVALENCE OF H. PYLORI IN DUODENAL ULCER PERFORATION

Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 28

Abstract

BACKGROUND Duodenal ulcer perforation is among common surgical emergencies. Recent data suggests that more than 99% of all duodenal ulcers having infection with H. pylori is associated with use of NSAIDS. There is a necessity to study the association of H. pylori infection with perforated duodenal ulcers. If proved, control of H. pylori may reduce this catastrophe and burden on the society. METHODS This study was conducted at Hi-Tech Medical College & Hospital, Bhubaneswar from December 2016 to October 2018. 30 cases were studied thoroughly according to the proforma. All the positive cases were given triple drug regimen (H. pylori kit) for a period of 14 days and negative cases were given omeprazole therapy for same period. Patients of duodenal ulcer perforation who were undergoing laparotomy for the same were selected. RESULTS Age wise distribution maximum i.e. 36.66% patients belonged to age group 41-50 yrs. In our study, incidence of H. pylori infection was 53.33-66.66%. Male: Female ratio was found to be 28:2. 15 and 19 out of 28 male patients showed presence of H. pylori with RUT & H. pylori antibody test respectively (i.e. incidence was 53.57% and 67.85%) and 1 out of 2 female patients showed positive RUT and H. pylori antibody test. CONCLUSIONS Incidence of H. pylori infection was 53% (RUT) and 66% (H. pylori antibody card test) in our study population. Maximum patients presented with hypovolemic shock, which was major cause of mortality and morbidity in our study group.

Authors and Affiliations

Gaurav Jha, Subrata Das, Sai Bharat Sunkara, Treena Minz, Saik Kasif Sahajada

Keywords

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EP ID EP668620
DOI 10.18410/jebmh/2019/386
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