Prevalence of H. Pylori in Dyspepsia Patients in a Tertiary Care Hospital of Bangalore
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Helicobacter pylori (H. Pylori) is the main risk factor for peptic ulcer, gastric associated lymphoid tissue and gastric adenocarcinoma. Several studies have revealed H. Pylori association in 70-75% cases of dyspepsia. H. Pylori is found in 80-100% of duodenal ulcers and 60-75% of gastric ulcers. With this background, a study was conducted to document prevalence of H. pylori in dyspepsia patients in a tertiary care hospital. Material and Methods: A cross sectional study was conducted in a tertiary care hospital in Bangalore from January 2015 to December 2015 on 100 purposively selected dyspepsia patients attending Medicine Outpatient department (OPD). Presence of H. Pylori was confirmed after histopathology and microbiological investigations of the endoscopy biopsy sample. Data was entered in Microsoft excel and analysed using Open Epi software. Descriptive statistics and chi square test was applied. Results: Three fourth (75%) of the study participants were males. The mean age of the study participants was 39.25±10.87 years. All the patients presented with upper abdominal pain (100%) followed by nausea/vomiting (94%). Endoscopic findings revealed that three fifth (60%) of the patients had ulcer dyspepsia and two fifth (40%) of them had non ulcer dyspepsia. About 68% of the patients were infected with H. Pylori. A significant association was found between H. Pylori and duodenal ulcers (p 0.001). Conclusion: The overall prevalence of H. Pylori infection in patients of dyspepsia was 68%. The prevalence of H. Pylori was higher in ulcer dyspepsia patients. There was a significant association between H. Pylori and duodenal ulcers (p 0.001).
Authors and Affiliations
Shanthi Kumari B, Gargi Singh Thakur, Sumana Y
Keywords
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