Prevalence of Hepatitis A Virus and Hepatitis E Virus in Western Thar Region
Journal Title: National Journal of Laboratory Medicine - Year 2017, Vol 6, Issue 4
Abstract
Introduction: Hepatitis A Virus (HAV) and Hepatitis E Virus (HEV) pose major health problems in India. Both viruses are enterically transmitted, resulting in Acute Viral Hepatitis (AVH) in developing countries. This study was done to determine prevalence of HAV and HEV and their co-infection in patients presenting with AVH in a tertiary care hospital. Aim: To determine the prevalence of HAV and HEV and their co-infection among patients attending a Tertiary Care Hospital in Jodhpur presenting with symptoms of acute hepatitis. Materials and Methods: A cross-sectional study of one year duration was conducted in the Department of Microbiology, Dr S.N. Medical College, Jodhpur. A non random sampling of 174 patients presenting with AVH was considered in the study. On the basis of history, serum samples were analyzed for IgM anti-HAV and IgM anti-HEV for the detection of HAV and HEV, respectively using commercially available ELISA kits. Data collected was analysed by using Statistical Package for the Social Sciences (SPSS) version 11 and p-value <0.05 was considered significant. Results: The seroprevalence of HAV and HEV positive patients were 13.79% and 4.02%, respectively. The seroprevalence of both HAV and HEV in patients with AVH was 1.15%. The prevalence of HAV and HEV among males (58.3% and 41.6%) was higher than in females (7.97% and 14.28%). Conclusion: The prevalence of HAV is higher than that of HEV but screening of HEV should be done as there are cases of coinfections. In this region of country, these data will play a role in planning of vaccination strategies and for better sanitation programme in future.
Authors and Affiliations
Prabhat Kiran Khatri, Dallaram Seervi, Vikrant Negi, Laxmi Rathore, Saroj Meena
Keywords
Related Articles
- EP ID EP376965
- DOI 10.7860/NJLM/2017/31642:2260
- Views 113
- Downloads 0
Detection of Anti-ABO Antibodies Titres Prior ABO Incompatible Renal Transplantation using Indirect Antihuman Globulin Test via Tube Incubation and Gel Column Technique
Introduction: Renal transplantation is the ideal treatment for patients with End Stage Renal Disease (ESRD). Nowadays, ABO incompatible renal transplant give encouraging results. It reduces the waiting time of patients o...
Tracheal Agenesis and Tracheal Stenosis in Perinatal Autopsies: A 13-Year Study
ABSTRACT Introduction: Tracheal agenesis and tracheal stenosis are rare, fatal congenital anomalies and are an acute neonatal emergency. It may be an isolated anomaly or may be associated with other congenital anomalies....
Hepcidin- A Burgeoning Biomarker
The discovery of hepcidin has triggered a virtual ignition of studies on iron metabolism and related disorders. The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism. The synthesis of hepcidin is...
Basic Haematological Scoring System-Is it the most Accurate Neonatal Sepsis Predictor?
Introduction: Sepsis in neonates contributes for approximately 15% of the neonatal mortality in India. Even though a positive blood culture is pertinent for diagnosis, the technique is time consuming and is positive in o...
Immunophenotypic and Morphological Profile of Basal like and non Basal like Invasive Breast Carcinoma
Introduction: Breast carcinomas are heterogeneous disease with different prognosis and therapy responses despite similarities in histological types, grade and stage. Recently, gene expression profiling, a method using cD...