Prevalence of Hepatitis A Virus and Hepatitis E Virus in Western Thar Region
Journal Title: National Journal of Laboratory Medicine - Year 2017, Vol 6, Issue 4
Abstract
Introduction: Hepatitis A Virus (HAV) and Hepatitis E Virus (HEV) pose major health problems in India. Both viruses are enterically transmitted, resulting in Acute Viral Hepatitis (AVH) in developing countries. This study was done to determine prevalence of HAV and HEV and their co-infection in patients presenting with AVH in a tertiary care hospital. Aim: To determine the prevalence of HAV and HEV and their co-infection among patients attending a Tertiary Care Hospital in Jodhpur presenting with symptoms of acute hepatitis. Materials and Methods: A cross-sectional study of one year duration was conducted in the Department of Microbiology, Dr S.N. Medical College, Jodhpur. A non random sampling of 174 patients presenting with AVH was considered in the study. On the basis of history, serum samples were analyzed for IgM anti-HAV and IgM anti-HEV for the detection of HAV and HEV, respectively using commercially available ELISA kits. Data collected was analysed by using Statistical Package for the Social Sciences (SPSS) version 11 and p-value <0.05 was considered significant. Results: The seroprevalence of HAV and HEV positive patients were 13.79% and 4.02%, respectively. The seroprevalence of both HAV and HEV in patients with AVH was 1.15%. The prevalence of HAV and HEV among males (58.3% and 41.6%) was higher than in females (7.97% and 14.28%). Conclusion: The prevalence of HAV is higher than that of HEV but screening of HEV should be done as there are cases of coinfections. In this region of country, these data will play a role in planning of vaccination strategies and for better sanitation programme in future.
Authors and Affiliations
Prabhat Kiran Khatri, Dallaram Seervi, Vikrant Negi, Laxmi Rathore, Saroj Meena
Keywords
Related Articles
- EP ID EP376965
- DOI 10.7860/NJLM/2017/31642:2260
- Views 119
- Downloads 0
Demonstration of Virulence Factors in Streptococcus Pneumoniae Isolates from a Tertiary Hospital in South India
Introduction: Streptococcus pneumoniae (pneumococci) colonizes the nasopharynx and 94 different serotypes have been characterized on the basis of the capsular polysaccharides. Nasopharyngeal colonization is documented to...
Quality Assurance Program in Clinical Biochemistry Laboratory at a Multispeciality Teaching Hospital, with Special Reference to Quality Indicators
ABSTRACT Introduction: Clinical laboratories have made considerable progress in addressing the needs of quality control, to make a difference in patient care by giving reliable results. With high degree of dependence on...
Extra-Pulmonary Tuberculosis Presenting as Established Non-Union Tibia Shaft Fracture
Extra-pulmonary tuberculosis (EPTB) is a great mimicker as it can present extraordinarily as a non-resoluting inflammatory pathology or can even mimic as malignancy especially sarcomatous or metastatic deposits. It somet...
Chryseobacterium indologenes Bacteraemia in a Man with Oesophageal Cancer: A Case Report
Chryseobacterium indologenes is a rare pathogen of the humans and is normally found in the environment in soil, plants and foodstuffs. Infections caused by C. indologenes have been reported as a cause of serious infectio...
Application of Probabilistic Approach in Reporting Breast Lesions on Fine Needle Aspiration Cytology: Institutional Study
Introduction: Cancer of breast is among the most common cancer throughout the world. In Indian women rising incidence of breast cancer remains a concern. Due to lack of health awareness and limited breast cancer screenin...