PREVALENCE OF HUMAN PAPILLOMA VIRUS AND ITS ASSOCIATED RISK FACTORS IN WOMEN WITH ABNORMAL CYTOLOGY AT A TERTIARY CARE HOSPITAL OF NORTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 89
Abstract
BACKGROUND Cervical cancer is the fourth most common cancer worldwide. High-risk Human Papilloma Virus (HPV) infection is an important event in the progression of cervical cancer. The most common HPV types associated with pre-invasive and invasive cervical lesions are HPV 16, 18, 31, 33 and 45. As anogenital HPV infection is transmitted by sexual intercourse, sexual behaviour patterns among women and their partners often dictate women’s risk for HPV infection and acquisition. Aim of this study was to know the prevalence of HPV and its associated risk factors in women with abnormal cytology. MATERIALS AND METHODS The samples were processed for DNA extraction and finally amplification of this DNA was done with the help of PCR system using specific primers for the detection of HPV DNA. Study Design- We performed a prospective observational study on 50 clinical samples of cervical scrapings from women with abnormal cytology. RESULTS In our study, prevalence of HPV came out to be 28 percentage. Early age at marriage, multiple sexual partners, use of OCPs, multiparity were found to be significant risk factors for HPV infection. CONCLUSION Our study concluded that younger age at marriage, multiple sexual partners, multiparity, use of OCPs are the most important risk factors for the acquisition of HPV infection.
Authors and Affiliations
Bhawna Bhawna, Kanwardeep Singh, Loveena Oberoi, Pusha Devi
Keywords
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- EP ID EP277928
- DOI 10.14260/jemds/2017/1341
- Views 74
- Downloads 0
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