SOLID PSEUDOPAPILLARY TUMOUR OF THE PANCREAS- A SINGLE INSTITUTION STUDY OF THREE CASES WITH A BRIEF REVIEW OF LITERATURE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 4
Abstract
BACKGROUND Solid Pseudopapillary Tumour (SPT) of the pancreas is a distinctive tumour of low malignant potential with a predilection for females in the second and third decades of life. We report here 3 cases because of its rarity and we attempt to briefly review the literature of this distinctive lesion. MATERIALS AND METHODS A total of 3 cases were diagnosed and treated in our institute over a 2-year period. A retrospective study of these cases was performed with respect to age group most frequently affected, sex ratio, common presenting symptoms and signs, investigative protocols, pathological features, treatment offered, outcome and prognosis. All the three patients were females with the age of presentation of 20 yrs., 14 yrs. and 15 yrs. respectively. The commonest presenting symptom was abdominal pain. The patients underwent distal pancreatectomy, Whipple’s resection and pancreaticoduodenectomy with appendicectomy respectively. Histological diagnosis was made by performing haematoxylin-eosin staining and confirmed by immunohistochemistry. RESULTS All the patients were females in the age group of 13 - 25 years. Pre-operative imaging is not diagnostic. Pathological examination is the mainstay in the diagnosis. No metastasis or recurrence was detected during followup. CONCLUSION Solid pseudopapillary tumour of the pancreas is a rare entity, therefore proper diagnosis, evaluation and formulation of treatment protocols is difficult. A high index of clinical suspicion is necessary to suspect and diagnose it. Surgical excision offers the best chance for cure and should always be attempted irrespective of the magnitude of the resection involved. The results of immunohistochemical and ultrastructural studies indicate that it must be regarded as a tumour of uncertain histogenesis and undetermined differentiation.
Authors and Affiliations
Zeenat Sarmadi Imam, Reecha Singh, Bipin Kumar, Kalpana Chandra, Mona Lisa
Keywords
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- EP ID EP285870
- DOI 10.14260/jemds/2018/120
- Views 53
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