Prevalence of human T-lymphocyte leukemia virus among blood donors in Guangzhou
Journal Title: Chinese Journal of Blood Transfusion - Year 2025, Vol 38, Issue 2
Abstract
[Objective] To analyze the prevalence of human T-lymphocyte leukemia virus (HTLV) among blood donors in Guangzhou from 2016 to 2021, and provide a basis for blood collection and supply management in this region. [Methods] A total of 2 116 951 voluntary blood donors were screened for anti-HTLV by enzyme-linked immunosorbent assay (ELISA) from March 2016 to December 2021 in Guangzhou, and the reactive cases were further confirmed by Western blotting (WB). Qualitative data were analyzed by χ2 with spss19 software. The trend of the total positive rate of HTLV confirmation test by WB from 2016 to 2021 was analyzed with the Joinpoint software, and the annual percent change (APC) was used to determine whether the trend changes were statistically significant. [Results] From March 2016 to December 2021, the total positive rate for anti-HTLV by ELISA among voluntary blood donors in Guangzhou was 0.019 7% (416/ 2116 951), and the WB confirmed positive rate was 0.001 1% (23/2 116 951). The total positive rate of HTLV among individual voluntary blood donors in the six main districts (0.002 12%, 19/895 301) was higher than that among group voluntary blood donors (0.000 32%, 3/951 947) (P<0.05). There was no significant difference in the total positive rate of HTLV confirmation between the six main districts (0.001 19%) and the three non-main districts (0.000 37%) (P>0.05). The trend of the total positive rate of HTLV infection in the six main districts and the Guangzhou area(including the six main districts and three non-main districts) showed no significant increase or decrease. [Conclusion] The prevalence of HTLV among blood donors in Guangzhou remains at a low level.
Authors and Affiliations
Yuxiao LI, Xia RONG, Bo HE, Rongsong DU, Zhengang SHAN, Qiao LIAO
Keywords
Related Articles
- EP ID EP760106
- DOI 10.13303/j.cjbt.issn.1004-549x.2025.02.010
- Views 13
- Downloads 0
Survey of knowledge acquisition for blood transfusion of medical staff in Wuwei: an underdeveloped city in western China
Objective To investigate the knowledge acquisition status for blood transfusion of transfusion related medical staff in underdeveloped cities in western China and explore its influencing factors. Methods A questionnaire...
Enhancing the sensitivity of HIV DNA detection: a magnetic bead-based method
Objective To establish a magnetic bead enrichment strategy for the detection of human immunodeficiency virus deoxyribonucleic acid (HIV DNA) in peripheral blood, and to verify the improvement of the sensitivity of this m...
Transfusion efficacy and influencing factors of patients transfused with different therapeutic doses of platelets: a comparative analysis
[Objective] To compare and analyze the efficacy of platelet transfusion in patients with different doses, and to analyze the risk factors for platelet transfusion refractoriness. [Methods] A total of 5 827 patients who r...
Identification of mimicking anti-Ec with literature review: a case report
[Objective] To identify a mimicking alloantibody, analyze its serological characteristics and antibody specificity, and explore transfusion strategies for mimicking alloantibody. [Methods] The antibody specificity of pat...
The treatment of refractory wounds with apheresis platelet-rich plasma
Objective To explore the model of treatment of refractory wounds by apheresis platelet-rich plasma (PRP), and evaluate its efficacy and safety. Methods PRP treatment was carried out for 34 patients with refractory wounds...