PREVALENCE OF MYCOBACTERIUM TUBERCULOSIS AMONG SMOKERS
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2018, Vol 7, Issue 2
Abstract
The convergence of these two important health hazards is likely severely affecting India’s TB control programs. This study was carried out to determine the prevalence of smoking in newly diagnosed pulmonary TB patients and the impact of smoking on disease outcomes in a tertiary care hospital. All patients newly diagnosed with pulmonary TB as per the Revised National Tuberculosis Program of India (RNTCP) 2013 criteria were enrolled in the study. On the basis of their self-reported smoking status, the participants were classified as never smokers, current smokers, and ex-smokers. Patients were started on anti-TB treatment and were followed for 2 years. Among the 2350 subjects (1,758 males and 592 females), 1,593 patients (67.78%) were never smokers. Current and ex-smokers numbered 757 (32.21%), of which 751 (31.95%) were males and 6 (0.26%) were females. Smoking was associated with more extensive lung disease, lung cavitation, and positive sputum smear and culture results at baseline. In both current smokers and ex-smokers, sputum smears and cultures were significantly more likely to remain positive after 2 months of treatment. Ex-smokers and current smokers had significantly high rates of defaults, treatment failures, and relapses. The prevalence of smoking is very high in TB patients. Tobacco smoking is associated with a considerably increased risk of advanced and more severe disease in the form of lung cavitations, positive sputum smear and culture results, and slower smear and culture conversion after initiation of treatment. Key words: Smoking, Tuberculosis, mycobacterium tuberculosis.
Authors and Affiliations
Rupal Sengar
Keywords
Related Articles
- EP ID EP487216
- DOI -
- Views 132
- Downloads 0
Self-medication and role of pharmacist in patient education
Introduction: Pharmacy is the art, science and practice of preparing, preserving, compounding and dispensing of drugs and it also includes modern services related to health care including clinical services, reviewing med...
Indigenous Uses of Economically and Commercially important Medicinal Plants Use to Cure Gynecological Diseases by Ethnic People of Bodmalla Village, Almora District of Western Himalaya, India
Plants have been used as a source of medicines from ancient times to the present day. Initially this constituted folk or ethno medicine practiced in India, China, Middle East, Africa and South America. Later considerable...
Optimization and validation of RP-HPLC method for the estimation of chlorzoxazone and paracetamol with its genotoxic impurity (4-amino phenol) in bulk and pharmaceutical drug product using PDA detector
A simple, accurate, precise, reproducible RP-HPLC method has been developed for simultaneous estimation of chlorzoxazone (CZX) and paracetamol (PCM) with its genotoxic impurity, p-amino phenol (4-AP) in bulk and combined...
PHENYTOIN INDUCED TOXIC EPIDERMAL NECROLYSIS; A CASE REPORT
Several drugs are at high risk of causing Toxic Epidermal Necrolysis (TEN) including Anti-convulsants such as phenytoin, carbamazepine and phenobarbital. Other drugs include antimicrobials like sulfonamides followed by N...
REVIEW ARTICLE ON STEVENS JOHNSON SYNDROME
Stevens-Johnson Syndrome (SJS) is rare, cutaneous, severe, drug-induced hypersensitivity reactions marked by widespread inflammation of the epidermis, ending in necrosis and the eventual sloughing of tissue.It is the syn...