Prevalence of Non Alcoholic Fatty Liver Disease and Its Association with Cardio Metabolic Diseases in Early Diabetics
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 9
Abstract
Background: To study the prevalence of non-alcoholic fatty liver disease and its association with cardiometabolic diseases in early diabetics. Materials and Methods: The Study was conducted on 120 diabetic patients attending the outdoor patient department and in wards of Department of medicine and diabetic clinic S.N. Medical College, Agra during the period from March 2016 to Aug 2017. After taking informed consent from the patients a detailed history physical examination and laboratory investigations carried out. NAFLD was diagnosed on the basis of ultrasonic assessment of the liver. Results: The prevalence of NAFLD in diabetics was 56.67%. NAFLD patients were associated with metabolic syndrome components like hypertension (52.94%) (p-value=0.8045), diabetic dyslipidemia (73.53%) (p-value=0.0022), central obesity(70.58%) (p-value=0.0165), hypothyroidism (23.53%) (pvalue=0.0005), hyperuricemia (20.58%) (p-value=0.0001), and deranged transaminases (47.05%) (pvalue=o.8045). NAFLD patients were also associated with cardiac components like left ventricular hypertrophy (23.53%) (p-value=0.0005), systolic dysfunction (20.58%) (p-value=0.0001), diastolic dysfunction (17.65%) (p-value=0.0001), and increased carotid intima-media thickness (29.41%) (pvalue=0.0081). Conclusion: The patients of diabetes mellitus should undergo liver function tests, ultrasonography of liver, Fibroscan and 2D echocardiography at the time of diagnosis. Early detection would help not only in modifying the disease course but would also delaying or preventing the fatal complications like steatosis, steatohepatitis, cirrhosis, and carcinoma of the liver. Accordingly the patient may be treated earliest by various measures like lifestyle modifications etc.
Authors and Affiliations
Dr Ram Prakash Pandey
Keywords
Related Articles
- EP ID EP515341
- DOI -
- Views 59
- Downloads 0
Echocardiographical Evaluation and Cardiovascular Changes in Patients Admitted in ICU with Acute Respiratory Failure of Various Etiology in Tertiary Care Hospital
Introduction: Acute respiratory failure is a life-threatening condition characterized by an inability to maintain normal levels of oxygen and/or carbon dioxide due to dysfunction of the respiratory system. Cardiac and re...
Echocardiography Profile in HIV Patients and Its Correlation with CD4 Count and who Clinical Staging
With the global epidemic of HIV, developing countries like India are having a rapid surge in the number of HIV cases. An effective strategy needs to be formulated for the management of HIV which has multisystem involveme...
Prognostic Value of Gravin Versus Survivin Gene Expression in a Cohort of Egyptian Patients with Adult Acute Myeloid Leukemia
Despite recent progress in diagnosis and management, acute myeloid leukemia still remains a highly fatal disease which invites the needs for accurate predictors of clinical outcome. The aim of the present study was to ex...
Effect of Specific Yogasanas on Volunteers Having Cardiovascular HyperReactivity to Cold Pressor Test
According to the World Health Organization, stress is a significant problem of our times and affects both physical as well as the mental health of people. Stress coping methods are the cognitive, behavioral and psycholog...
Height and Weight Adjusted Dose versus Fixed Dose of Bupivacaine for Spinal Anaesthesia for Caesarean
Spinal Anaesthesia is the preferred choice of anaesthesia for caesarean sections. It avoids the risks associated with general anaesthesia like the risk of aspiration, incidence of difficult airway etc. However it is not...