Prevalence of Plasmodium and Salmonella Species from Patients Attending University Clinic and Hospital in Nigeria
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Background: Since 2013 till date, Malaria and Typhoid fever has been the major cause of fever for consultation in health centers. Epidemiological, Cultural and Drug Sensitivity Prospective study spanning 4 years was conducted in Unijos Health Services, this study purposed to describe and document the findings of the epidemiology and drug sensitivity pattern of Plasmodium species and Salmonellosis as evidence base data for the eradication of Malaria and Typhoid fever in Nigeria and the world at large.Method: Two hundred and fifty patient’s blood and stools samples were diagnosed; age, gender, microscopy, culture and sensitivity were the variables, the drug effects of P-Alaxin, Artemether Lumefantrine and Artesunate Amodiaquine was determined. Similarly, the in-vitro effects of ciprofloxacin, cefuroxime and azithromycin and their synergic activities also determined. Result: The prevalence of Plasmodium and Salmonella species studied, unveiled the malaria positive cases of 193 (77.2%) while cases of Typhoid recorded 59 (23.6%). The age group of 16-26 years reviled highest incidence in both cases. Conclusion: Fever caused by malaria and typhoid was highest among female young adult, these representing strong evidence in addition with microscopic and cultural results obtained. Artemether Lumefantrine and ciprofloxacin were discovered to be the most effective, even exhibiting drug curative synergistic action. The ANOV reviled significant statistical difference (P < 0.05) among the drugs used.
Authors and Affiliations
Nwosu A. O. , Agbo E. B, Uba . A
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