Prevalence of pseudoexfoliation syndrome among adults in Melmaruvathur
Journal Title: Medpulse International Journal of Ophthalmology - Year 2018, Vol 8, Issue 2
Abstract
Aim: To determine the association of glaucoma in pseudo exfoliation syndrome, assess the status of blood aqueous barrier and to analyze the protein concentration in aqueous histo pathological changes in lens and trabecular meshwork in pseudo exfoliation syndrome. Methodology: A Prospective study of 100 patients with exfoliation syndrome who attended the OPD, department of Ophthalmology in MelmaruvathurAdiparasakthi institute of medical sciences between November 2015 and December 2017 were included in the study.All the patients were subjected to a detailed slit-lamp examination and Glaucoma workup was done for all the patients which included Gonioscopy with Goldmann Two mirror lens, Tonometry with Goldmaan applanation tonometer, Perimietry with Bjerrum’s screen and Octopus 1-2-3 automated perimeter in selected cases. Results: Out of the 100 patients included, bilateral exfoliation was more common. Mean age of PXF was 64.5 years. 77% of patients had glaucoma of which open angle glaucoma accounted for 56 and angle closure glaucoma 21. Nuclear cataract had a more common incidence with exfoliation. Impairment of blood aqueous barrier is evidenced by rise mean aqueous protein and fluorescein dye leakage in angiography. On electron microscopic study shows duplication of basement membrane and intimate association of exfoliation material with basement membrane. Conclusion: Bilateral exfoliation was more common than unilateral. Exfoliation syndrome is definitely a risk factor for the development of glaucoma. The impairment of blood aqueous barrier is one of the pathognomonic features ofexfoliation syndrome.
Authors and Affiliations
M J Venkatesan, R Rajeshkannan
Keywords
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