Prevalence of Rotavirus Infection in Infants and Young Children with Gastroenteritis in Two North-East States, Nigeria
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 20, Issue 2
Abstract
Introduction: Rotavirus, is an eleven segmented double stranded ribonucleic acid virus in the family of Reoviridae, and is a leading cause of gastroenteritis among infants and young children. Aims: This study was aimed at conducting a preliminary survey of rotavirus antigen in diarrheic stool of children (< 5 years) in Taraba and Yobe states in Nigeria to determine the prevalence. Methodology: One hundred and fifty children, each, in two north east states (Taraba (TR) and Yobe (YB) Nigeria with acute diarrhea were selected by random sampling in a cross-sectional, hospital-based study. Fifty two non-diarrheic and three hundred diarrheic tool samples from children less than five years old were assayed for rotavirus antigen by enzyme linked immunosorbent assay (Cortez Diagnostic Automation, Inc, USA) kit. Demographic data of the children were collected and result analysed using chi-square. Result: All non-diarrheic stool (n=52) were negative for rotavirus antigen while of the total of 300 children sampled, overall prevalence of 4.0% and 9.3% were obtained in Taraba (mean age = 25.85months) and Yobe (mean age = 25.65months) respectively. Type of toilet used in both states was a factor in infection (TR p=0.007; YB p=0.00004). There was preponderance of infected male over female children in both states but this was not significant (p=0.55; p=0.48). Also, the source of drinking water had no significant effect on the prevalence of infection in both states (TR: p=0.177; YB: p=0.134). Playing with toys was found to serve as a predisposing factor of infection in Yobe state only (p=0.001). Conclusion: The result of this study shows that rotavirus is a significant aetiologic agent of diarrhea among infants and young children in the study area. Public enlightenment on the predisposing factors to infection should be emphasized in order to mitigate transmission. Also, determination of the circulating genotypes in the study area is recommended.
Authors and Affiliations
Samuel O. Oyinloye, John Idika, Mahdi Abdullahi, Mohammed A. Lawan, Abdulrazak Dahiru, Aisha Salihu
Keywords
Related Articles
- EP ID EP311457
- DOI 10.9734/BJMMR/2017/22773
- Views 74
- Downloads 0
Profound Study for Functions of Antimicrobial Peptides in Prevention of Oral Disease
Antimicrobial peptides (AMPs) have a widespread distribution in human body and have antimicrobial activity against microorganisms with wide-range class of host-defense molecules. These are small cationic peptides that p...
Marked Weight Loss, Muscle Wasting and Fatigue on Administration of Empagliflozin in a Subject with Type 2 Diabetes
Background: Weight loss, fatigue and decreased quality of life are frequently reported at the time of initial diagnosis by subjects with Diabetes Mellitus of both types although far more frequently with type 1 and are at...
Evaluation of Reaction Pattern of Skin Diseases in Oman: A Study Based on Immunofluorescence and Light Microscopy Investigation Only
Aims: The aim of this study was to evaluate various reaction pattern of skin diseases in Oman using immunofluorescence and light microscopy investigation only. Methodology: A total of 187 skin biopsies were retrospecti...
Ineffective Erythropoiesis: Associated Factors and Their Potential as Therapeutic Targets in Beta-Thalassaemia Major
Beta-thalassaemia (-thal.) is single-gene disorder that exhibits much clinical variability. -thal. major is a major health problem, and the only method of curing is allogenic bone-marrow transplantation, which is not a...
Proper Medical Prescriptions and Cord Blood Harvesting Improvement at a Children’s Hospital of North Eastern Italy
A systematic harvesting of hematopoietic progenitor cells for transplant purpose in oncology begun in Friuli Venetia Giulia (FVG), a region of north east Italy, at the end of 2000. The actual economic crisis in Italy and...