Temporal Trends in Radiation Exposure and Utilization of Coronary CT Angiography, SPECT, and Invasive Coronary Angiography

Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 17

Abstract

Background: The use of noninvasive medical imaging has increased over the past decade at a cost of significant lifetime radiation exposure to study subjects. We report the implementation of radiation dose reduction methods and associated reduction in ionizing radiation exposure with Coronary Computed Tomography Angiography (CCTA) over time. Methods: Radiation doses and total number of studies performed were evaluated constantly from January 2010 to September 2012 for CCTA (N=2613), as well as Single photon emission computed tomography (SPECT, N=8060) part of an ongoing effort to minimize radiation exposure. Analysis of variance was used to evaluate the radiation exposure reduction among modalities. We compared CCTA radiation doses in the era of retrospective protocols coupled with dose modulation (40%-80%phase) using Siemens® 64-slice Dual Source technology, with prospective scanning on the same equipment, as well as radiation doses on the newer Siemens® Flash Equipment and the implementation of nursing/technologist aggressively driven protocol for heart rate control and image acquisition independent of imaging provider presence during acquisition. Results: The radiation dose reduction with implementation of multiple measures of radiation reduction to include physician independent-technician driven CCTA protocol resulted in a reduction from mean of 9.85±5.96 (median 8.8mSv) to mean of 3.00±2.53(median 2.1mSv) (p<0.0001). CCTA radiation dose has decreased by 69.2% since January of 2010 while SPECT radiation dose remained constant at 14mSv (p<0.0001). Conclusion: Continued advances in software and hardware technology, combined with “physician independent-technician driven” CCTA protocol have drastically reduced radiation dosing in CCTA to annual background radiation exposure, while maximizing the benefit of the study and without sacrificing patient safety.

Authors and Affiliations

Ronald L. Jones, Richard A. Clark, Bernard J. Rubal, Ryan J. McDonough, Kenneth Stone, Edward A. Hulten, Todd C. Villines, Ahmad M. Slim, Kevin E. Steel

Keywords

Related Articles

Predicting Postprandial Oxidative Stress Using Serum Triglycerides Following Oral Fat Tolerance Testing

Background: The topic of postprandial oxidative stress continues to receive considerable attention, with elevations in oxidative stress biomarkers associated with human disease (e.g., insulin resistance, atherosclerosis)...

Classic Genotypes of the ACE Gene do Not Interfere in Blood Pressure Responses to Reactivity Test in Male Adolescents

Background: The Angiotensin Converting Enzyme (ACE) is responsible for converting Angiotensin I into Angiotensin II, which has vasoconstrictive properties. Polymorphisms in the ACE gene have been associated to higher lev...

Anti-cell Proliferative, Anti-inflammatory and Anti-angiogenic Potential of Lupeol in 7,12-dimethylbenz(a) Anthracene Induced Hamster Buccal Pouch Carcinogenesis

Aim: Diverse pharmacological and biochemical effects of lupeol have been reported earlier. The present study utilized the immune expression pattern of proliferating cellular nuclear antigen (PCNA), cyclin D1, vascular en...

A 66 Patient Multi-Institution Phase IV Post-Authorization Surveillance of ProThelial™ (High Potency Polymerized Cross-linked Sucralfate) -Single Agent Efficacy for the Prevention and Rapid Reversal of Chemo-radiation Induced Oral, Esophageal and Intestinal Mucositis

Background: Standard potency sucralfate is not recommended by most clinical guidelines for prevention or treatment of oral and intestinal mucositis. However, its polymerized cross-linked (thereby high potency) formulatio...

Prevalence and Factors Associated at Presence of Central Nervous System Congenital Malformations

Introduction: Congenital malformations are currently an important cause of morbidity and mortality in many countries, though in most cases their etiology is unknown. The central nervous system (CNS) is involved in many o...

Download PDF file
  • EP ID EP349505
  • DOI 10.9734/BJMMR/2014/9394
  • Views 36
  • Downloads 0

How To Cite

Ronald L. Jones, Richard A. Clark, Bernard J. Rubal, Ryan J. McDonough, Kenneth Stone, Edward A. Hulten, Todd C. Villines, Ahmad M. Slim, Kevin E. Steel (2014). Temporal Trends in Radiation Exposure and Utilization of Coronary CT Angiography, SPECT, and Invasive Coronary Angiography. Journal of Advances in Medicine and Medical Research, 4(17), 3384-3392. https://europub.co.uk/articles/-A-349505