Prevalence of Seropositivity for Human T lymphocytes Virus in Patients with Hereditary Bleeding Diseases in Population of West Azerbaijan

Journal Title: International Journal of Medical Laboratory - Year 2016, Vol 3, Issue 3

Abstract

Background and Aims: Human T-lymphotropic virus (HTLV) is a human retrovirus which has been known to cause adult T-cell leukemia/lymphoma and some other inflammatory disorders. Patients with hereditary bleeding diseases are at high risk for these viruses. In this study, we evaluated serological HTLV-I/II infection among these patients in west Azerbaijan of Iran. Material and Methods: We studied 50 hemophiliacs including 43 males and 7 females. Serum samples were screened for Anti-HTLV-I and II using enzyme-linked immunosorbent assay. Western blot method was applied on borderline results for confirmation. Results and Conclusions: All studied patients were seronegative for HTLV-I/II and serologic evidence of HTLV I/II infection was not found in any of patients. Based on our results, blood donor population of Urmia must be increased to achieve more accurate results.

Authors and Affiliations

Zakieh Rostamzadeh, Nasim Valizadeh, Mahshid Mohammadian

Keywords

Related Articles

The Effect of Methanol Extract of Echinops Lasiolepis on TNF-α Production in LPS-activated J774 A.1 Mouse Macrophages

background and Aims: Plants as medicines have always played a vital role in human life. Tumor necrosis factor alpha (TNF)-α is one of the macrophage-derived inflammatory cytokine with pleotropic effects in the infl...

Frequency of FLT3 ITD and FLT3 TKD Mutations in Multiple Myeloma Patients (A Case Control Study)

Background and Aims: Multiple myeloma is a malignant proliferation of plasma cells derived from a single clone. The tumor, its products and the host response lead to organ damages. Some factors that are responsible in it...

Analysis of clbN and clbB genes in Isolated Klebsiella pneumonia of Biopsies from Patients with Colorectal Cancer

Background and Aims: Recently it has been proved that some of Enterobacteriacea like Klebsiella pneumoniae, which carry PKS islands, damage dsDNA by encoding Colibactin genotoxin; and finally they induce some apoptosis i...

Comparative Effect of Cinnamon Essential Oil, Diclofenac and Morphine on Acute and Chronic Pain in Mice

Backgrounds and Aims: Cinnamomum Zeylanicum is a medicinal herb used in Iranian traditional medicine as an analgesic spice, which its analgesic effect has been experimentally confirmed. Thus, this study was conducted to...

Effects of Zinc, Sodium and Potassium Metal Ions on Ammonium Fraction of Acid Phosphatase of Orange Fruit

Backgrounds and Aims: The purpose of this study was to examine the effects of potassium, sodium and zinc metal ions on ammonium sulfate fraction of acid phosphatase activity of orange fruit. Materials and Methods: Acid...

Download PDF file
  • EP ID EP212547
  • DOI -
  • Views 98
  • Downloads 0

How To Cite

Zakieh Rostamzadeh, Nasim Valizadeh, Mahshid Mohammadian (2016). Prevalence of Seropositivity for Human T lymphocytes Virus in Patients with Hereditary Bleeding Diseases in Population of West Azerbaijan. International Journal of Medical Laboratory, 3(3), 159-163. https://europub.co.uk/articles/-A-212547