Prevalence of Silent Coronary Artery Disease (CAD) in Asymptomatic T2DM – A Prospective Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 11
Abstract
Introduction: To detect the coronary artery disease at an early stage and also to correlate the various risk factors (age, sex, duration of diabetes mellitus, glucose lowering drugs, FBS, PPBS, HBA1C, Lipid profile, BMI and abdominal waist to hip circumference ratio) leading to coronary artery disease in asymptomatic Type 2 diabetic patients, in relation with treadmill test. Material and Methods: The present study was a crosssectional, prospective study conducted between 2016-17 on 82 asymptomatic T2DM patients, age >18yrs, with no clinical and ECG evidence of CAD. Results: Out of 82 cases of asymptomatic Type 2 diabetics patients, 32.9% were positive for TMT. The risk factors like age between 56 to 65 yrs (46%), males (36%), duration of diabetes > 15yrs (50%), cases on sulfonyureas and metformin combination (33%) and on insulin therapy (45%), BMI between 30 to 34.9 (70.83%), abdominal waist to hip ratio between 0.86 to 0.99 (30%), HbA1C more than 10% (44%), FBS more than 200mg/dl (42%) and, PPBS more than 350mg/ dl (58%), Total Sr. cholesterol level more than 240mg/dl (58%), T.G level more than 200mg/dl (53%), HDL levels less than 30mg/dl (47%) and HDL level between 31 to 45 mg/dl (23%), LDL level more than 160mg/dl (45%), VLDL more than 40mg/dl (50%), showed high percentage of positive treadmill test. Conclusion: Treadmill test being a non-invasive sophisticated screening test should be performed on all asymptomatic T2DM patients with high risk factors for early detection of asymptomatic CAD, to prevent catastrophic cardiac events and consequent deaths.
Authors and Affiliations
Shashidhar Prakash Khanapure, Devratsinh Parmar, Gopal Bajaj, Raghavendra Hanumanthappa Mural
Keywords
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