Prevalence of Silent Myocardial Ischemia in Patients with Type 2 Diabetes Mellitus and Related Factors
Journal Title: Turkish Journal of Endocrinology and Metabolism - Year 2000, Vol 4, Issue 3
Abstract
The aim of the study was to determine the prevalence of silent myocardial ischemia in type 2 diabetic patients without any clinical and/or laboratory findings of myocardial ischemia and to examine the related factors for silent myocardial ischemia. One hundred and sixteen (82 female, 34 male) type 2 diabetic patients with a disease duration of 5-20 years were included in the study. All patients underwent stress and resting myocardial perfusion single-photon emission computed tomographic study with 99mTc-MIBI. Coronary angiography was performed on patients with ischemia established by myocardial perfusion single-photon emission computed tomography. Ischemia was determined in 18 (15.5%) patients by myocardial perfusion singlephoton emission computed tomogr aphy and among 17 patients upon whom coronary angiography was performed 11 had coronary stenosis (>50%). Thus the prevalence of silent myocardial ischemia was 9.6%. The positive predictive value of myocardial perfusion single-photon emission computed tomography was calculated as 64.7% (77.8% for men and 50% for women). The mean diabetes duration of the patients with coronary stenosis was over 10 years. Significant relations were found between silent myocardial ischemia and male sex, high HbA 1C level and retinopathy. Patients (especially of the male gender and with a diabetes duration of over 10 years) with poorly controlled diabetes mellitus and/or with retinopathy should be screened for silent myocardial ischemia.
Authors and Affiliations
Mustafa Araz, Zeki Çelen, İlyas Akdemir, Vahap Okan, Alper Serçelik, Erkan Özbay
Keywords
Related Articles
- EP ID EP83176
- DOI -
- Views 128
- Downloads 0
The Effects of Hyperthyroidism on Lipid Peroxidation, Erythrocyte Glutathione and Glutathione Peroxidase
Previous studies have suggested that hyperthyroidism has some effects on lipid peroxidation and antioxidant systems. This study was designed to determine if lipid peroxid ation, glutathione, and glutathione peroxidase ca...
Editörden
Relationship of Early Atherosclerotic Vascular Changes with Serum Lipoprotein(a) in Predialysis Chronic Renal Failure and Maintenance Hemodialysis Patients
In renal failure studies revealed an increase in plasma concentration of lipoprotein(a)[ Lp(a)]. Elevated plasma Lp(a) levels in chronic renal failure patients is recognized as an independent risk factor for premature at...
Medial Arterial Calcification is a Predictor of Cardiac Autonomic Neuropathy in Diabetic Patients
Medial arterial calcification (MAC) is one of the complications of diabetes mellitus and recently, a relationship between cardiac autonomic neuropathy and MAC has been pointed out. By means of this relationship, we evalu...
Iodine Status and Thyroid Volumes of School Age Children From Northern Cyprus
In an epidemiological study carried out in eight different inland and coastal areas from the northern part of Cyprus 625 School Age Children (SAC) aged 9 and 10 years, underwent thyroid ultrasonography for determination...