Prevalence of Some Hematological Abnormalities among HIV Positive Patients on Their First Visit to a Tertiary Health Institution in Ethiopia; A Cross Sectional Study
Journal Title: International Blood Research & Reviews - Year 2014, Vol 2, Issue 6
Abstract
Aim: The main objective of this study was to identify the magnitude of hematological abnormalities among HIV patients on their first visit to antiretroviral treatment (ART) centers. Methods: A cross sectional study was conducted among 189 HIV positive patients, visiting University of Gondar Hospital, Ethiopia. Blood sample was analyzed for hematological parameters and CD4 count. Frequencies (%), mean (SD) or median (IQR) were used to summarize data according to the type of variable. Independent sample t-test and chi-square test were used as appropriate and in all cases P<0.05 was considered significant. Results: The mean (±SD) age of the participants was 33.2 (±9.3) years. The prevalence of anemia, leucopenia and thrombocytopenia were 42.3%, 4.8% and 12.7% respectively. Immunosupression was found in 83.1% of the individuals. CD4 count with leucopenia (P<0.0001) was the factor that showed significant association. Conclusion: The prevalence of hematological abnormalities in this study was high and nearly half of the patients were eligible to start antiretroviral therapy. Researches that explore the clinical presentations of HIV positive patients on their first visit to ART centers and hematological changes after initiation of treatment need to be conducted.
Authors and Affiliations
Zelalem Addis, Gashaw Yitayew, Belaynesh Tachebele
Keywords
Related Articles
- EP ID EP242581
- DOI 10.9734/IBRR/2014/11137
- Views 109
- Downloads 0
Cord Blood: A Review
The blood collected from a new born baby umbilical cord is known as Cord blood. It is a rich source of hemotopoietic stem cells, used in the treatment of over 80 diseases like various cancers and blood, immune and metabo...
Serum Levels of Gamma-interferon and Interleukin-4 in Homozygous Sickle Cell Anaemia Patients
Background: Impaired leucocytes functions is among mechanisms that have been reported to account for the immunocompromised state of patients with sickle cell disease. Objective: This study assessed cellular immunity usin...
Early Diagnostics of Beta Thalassemia Minor
Early diagnosis of disease is highly recommended for the treatment purposes by the clinicians. Thalassemia is a genetic disorder which can be inherited from the parents. Thalassemia is classified into two groups alpha th...
The Prevalence of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Students of Sultan Abdurrahaman School of Health Technology Gwadabawa, Sokoto, North-Western Nigeria
Background: The aim of this study was to determine the prevalence of the deficiency of Glucose-6-phosphate 10 dehydrogenase (G6PD) activity among students of Sultan Abdurrahaman School of Health Technology Gwadabawa, Sok...
Calotropis procera Extract Halts Plasmodium falciparum Transgression Through Red Blood Cell (RBC) Membrane
Aim: To evaluate the potential of Calotropis procera extracts in erythrocyte membrane stabilization with special emphasis on Plasmodium falciparum entry into RBCs. Place and Duration of Study: Department of Zoology, BMT...