Prevalence of Viral Hepatitis (A, B and C) among Haemophilic Children
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 4
Abstract
Haemophilia is a rare haematological disease characterized by prolonged bleeding due to defciency of coagulating factor 8 and factor 9. This is cross sectional study carried out at paediatric haematology unit Al-Azhar university hospital, Cairo, Egypt, and paediatric haematology unit of El Mabarah-Hospital-Health Insurance Organization, Zagazig, Egypt, during March 2014 to March 2016. One hundred male patients were screened for hepatitis (A, B, and C). Mean age was 11.47 ± 4.4 years old. About 95% with haemophilia A, 4% haemophilia B and 1 patient had combined haemophilia A and family history of hepatitis was 21%. Consanguinity was 28%. Similar condition in the family was 36%. Ecchymosis as clinical manifestation was 64%, haemarthrosis was 62% and jaundice detected in 35% of cases. Severity was mild 20%, moderate 47% and severe was 33%. Most affected joint was knee joint and represented 41%. Blood transfusion, cryoprecipitate were major risk factors for transmitting of hepatitis C positive cases. HAV was 7%, HBV was 0% and hepatitis C was 65%. Conclusion: HCV is still high in haemophilic and represent a major problem. Recommendation: Early detection, treatment, and further investigation of hepatitis C virus in haemophilic children.
Authors and Affiliations
Mohammed Salah Ali| Al-Azhar University, Cairo, Egypt, Corresponding e-mail: Roaarody721@gmail.com, Mohammed Sayed Hemeda| Department of Paediatrics, Faculty of Medicine, Al-Azhar University, Cairo, Egypt, Ahmed Mohesn Abd El-hakem| Department of Paediatrics, Faculty of Medicine, Al-Azhar University, Cairo, Egypt, Kamel Soliman Hammad| Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Keywords
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