Prevalence of weak D antigen and Rh positive and Rh negative blood groups among blood donors - A Six year experience in a blood bank of tertiary health care centre of central India
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 6, Issue 1
Abstract
Background: After ABO group system, Rh D is clinically one of the most important blood group systems. Testing of all Rh negative units (by routine method) is must to detect weak D antigen by IAT method. When test show agglutination with anti D and D (u) it is labelled as Rh (D) positive. If test show no agglutination it is labelled as Rh (D) negative. Objectives: To know the Prevalence of weak D antigen (Du) and Rh positive and Rh negative blood groups in blood donors of blood bank of tertiary health care centre of Bhopal (M.P). Material and Method: Retrospective study among donors blood samples of Rh negative by immediate spin tube method were tested for weak D by indirect antiglobulin test (IAT) by tube method. Observation and Results: Among 11607 healthy blood donors, 11131(95.89%) were RhD factor positive while, 476(4.09%) were RhD negative. Out of 476 RhD factor negative donors 05(0.04%) were weak D positive. The study conducted on donors of Blood Bank of Peoples College of Medical Science and Research Centre Bhanpur Bhopal (M.P) from January 2012 to December 2017. Conclusion: According to many studies weak D antigen is immunogenic and is capable of producing alloimmunisation if transfused to RhD negative subjects so weak D detection prevent alloimmunisation in Rh negative patients.
Authors and Affiliations
Reetesh Kumar Gujar, Upasana Uniya, Deepika Kirar
Keywords
Related Articles
- EP ID EP359865
- DOI -
- Views 122
- Downloads 0
A comparative study of bronchoalveolar lavage (BAL) cytology and transbronchial biopsy in the diagnosis of carcinoma of lung
Background: Respiratory tract cytology is a well established diagnostic tool in the evaluation of patient with suspected lung malignancy. Flexible fiberoptic bronchoscopy has revolutionized respiratory cytology, as bronc...
A study of head and neck lesions in a tertiary care hospital
Background: Head and neck lesions include a spectrum of pathological lesions ranging from simple benign to highly malignant entities. These lesions contribute significantly to morbidity and mortality of patients. Aims an...
Prevalence of weak D antigen and Rh positive and Rh negative blood groups among blood donors - A Six year experience in a blood bank of tertiary health care centre of central India
Background: After ABO group system, Rh D is clinically one of the most important blood group systems. Testing of all Rh negative units (by routine method) is must to detect weak D antigen by IAT method. When test show ag...
Knowledge, attitude and practices regarding voluntary blood donation
Background: The availability of safe and good quality blood is crucial in improving medical facilities in a society. A study on the KAP of the donors may prove to be useful in the successful implementation of the blood d...
A clinico-pathological study of urinary bladder epithelial neoplasms in a tertiary care hospital of Konkan region, Maharashtra
Background: Urinary bladder cancers are among the top ten reported cancers in India. Early diagnosis leads to prompt treatment as one tends to catch these tumors early in their formative stage. Objectives: 1.To study uri...