Prevalence of weak D antigen and Rh positive and Rh negative blood groups among blood donors - A Six year experience in a blood bank of tertiary health care centre of central India
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 6, Issue 1
Abstract
Background: After ABO group system, Rh D is clinically one of the most important blood group systems. Testing of all Rh negative units (by routine method) is must to detect weak D antigen by IAT method. When test show agglutination with anti D and D (u) it is labelled as Rh (D) positive. If test show no agglutination it is labelled as Rh (D) negative. Objectives: To know the Prevalence of weak D antigen (Du) and Rh positive and Rh negative blood groups in blood donors of blood bank of tertiary health care centre of Bhopal (M.P). Material and Method: Retrospective study among donors blood samples of Rh negative by immediate spin tube method were tested for weak D by indirect antiglobulin test (IAT) by tube method. Observation and Results: Among 11607 healthy blood donors, 11131(95.89%) were RhD factor positive while, 476(4.09%) were RhD negative. Out of 476 RhD factor negative donors 05(0.04%) were weak D positive. The study conducted on donors of Blood Bank of Peoples College of Medical Science and Research Centre Bhanpur Bhopal (M.P) from January 2012 to December 2017. Conclusion: According to many studies weak D antigen is immunogenic and is capable of producing alloimmunisation if transfused to RhD negative subjects so weak D detection prevent alloimmunisation in Rh negative patients.
Authors and Affiliations
Reetesh Kumar Gujar, Upasana Uniya, Deepika Kirar
Keywords
Related Articles
- EP ID EP359865
- DOI -
- Views 119
- Downloads 0
Fine needle aspiration cytology based on bethesda system for reporting thyroid among the population of Kollam
Background: Thyriod disorders are the most common endocrine disorders worldwide. The main purpose of FNA is to provide rational approach for management and determine the correct surgical procedure when surgery is require...
Histopathological study of lesions of nose, paranasal sinuses and nasopharynx at tertiary care centre
Background: A variety of non-neoplastic and neoplastic conditions involving the nasal cavity, paranasal sinuses (PNS), and nasopharynx are commonly encountered in clinical practice. Due to anatomical proximity of these d...
Clinicopathologic correlation of patients with lupus nephritis
Systemic Lupus erythromatosus (SLE) is an autoimmune disorder of unknown cause that can occur at almost any age, although it affects mostly women in second decade. The annual incidence of SLE is 50 to 70 per one million...
Evaluation of errors in clinical hematology practice
Background: Medical laboratory errors are one of the major factors that affect the diagnosis and future clinical course of management. These errors have a tremendous impact on patient safety and can translate into the ri...
Gastric mucosal changes in H. Pylori infection: A cross sectional study from Karnataka
Background: H. pylori has gained importance in the recent decades because of its association with gastrointestinal diseases such as chronic gastritis, gastroduodenal ulcers, mucosa associated lymphoid tissue lymphoma and...