A correlation study of clinical, biochemical and cytological profile in goitre - Our experience in Melmaruvathur tertiary health care hospital
Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 10, Issue 1
Abstract
Background: The diagnosis and management of goitre requires both Fine needle aspiration cytology and Thyroid function test. Objective: The purpose of this study was to assess the common presentation of thyroid lesion and to establish the correlation between clinical, biochemical, cytological findings to have a better idea about pathogenic mechanism behind thyroid pathology. Materials: This was a retrospective data analysis of 84 cases of thyroid lesions. All demographic, clinical, biochemical and cytological reports were collected from hospital laboratory records and statistically analysed. Results: Out of 84 cases studied, Females were predominant (92.9%) and predominant age group affected was between 21-50 years (n=69; 82.2%). The common clinical presentation was diffuse goitre (n=46; 54.8%) followed by solitary nodular goitre (n=31; 37%). Cytological diagnosis of colloid goitre was made for 40.5% cases and thyroiditis in 36.8% cases. Euthyroid status was seen in 60.7% cases. Clinical and cytological correlation showed 58.5% of diffuse goitre diagnosed as thyroiditis and 58.1% of solitary nodule as colloid goitre. Biochemical and cytological correlation showed 73.6% of thyroiditis with hypothyroid and 55% of colloid goitre with euthyroid level. Clinical and biochemical correlation showed 80.6% of solitary nodular goitre with euthyroid status. All the above correlations were statistically significant. (p<0.001). Conclusion: The common presentation was diffuse goitre and euthyroid status with female preponderance between 21-50 years of age. Most of the diffuse goitre were thyroiditis and associated hypothyroid status. Most of the solitary nodule were colloid goitre and associated euthyroid status.
Authors and Affiliations
Sumathi S, Ravichandran S
Keywords
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- EP ID EP591084
- DOI 10.26611/10510110
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