PrevalenceofHIV-TBCoInfectioninPatientsAttendingAntiretroviral Therapy CentreinaTertiaryCareHospital,Coimbatore.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Active/latent Tuberculosis in HIV infected individuals is termed co-infection.Worldwide around 1million cases of HIV have been affected with Tuberculosis and about 0.4million deaths have occured; more so in developing countries like Africa, India,etc.This study has identified various risk factors and assessed the prevalence of this co-infection in a tertiary care hospital. Materials and Methods:This hospital based retrospective study was done among 150 randomly selected HIV positive patients using their unique ART identification number.All HIV patients on ART irrespective of age, occupation,gender and treatment category were included in the study.Screening and diagnosis of Tuberculosis carried out by Acid fast Ziehl-Neelsen’s technique, Radiological findings and Mantoux test.Based on this they were categorised into Pulmonary and Extra-pulmonary tuberculosis.Correlation with CD4 counts by Partek was also done.Results:Among these 150 patients,24(16%)had HIV-TB co-infection and were in the sexually active age group 20-40yrs.A slight male preponderance (54%) as against 46% in females was noted. Majority were married(70%)and(58.3%)educated upto school level.Incidence was highest among manual labourers,drivers and unemployed.Low CD4 counts<200cells/microlitre were found in 62.5%.Pulmonary tuberculosis constituted 54% and Extra pulmonary 45.9%.Conclusion:This study found a prevalence of 16% HIV-TB co-infection in patients attending Antiretroviral Therapy centre.Heterosexual mode of transmission and drastic cultural changes indicate targeted behavioural modification could prevent further transmission.Effective implementation of awareness and control programs as envisaged by the Govt. of India and the State health authorities along with NGOs and private sector could help in formulating further interventional measures to reduce the prevalence of HIV-TB coinfection andthereby reduce the disease burden.
Authors and Affiliations
N. Mythily, Ashok Kumar C
Keywords
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- EP ID EP374268
- DOI 10.9790/0853-1705032123.
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