Primary Anal Canal Mucinous Adenocarcinoma: About Two Cases And A Review of The Literature
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Introduction: Anal tumors are rare neoplasms of the digestive tube that represent 1,5% of gastrointestinal tumors. They present a more aggressive natural history, with shorter survival times and higher rates of local as well as distant relapse. It is difficult to distinguish from adenocarcinoma of the lower rectum unvading the anal canal. Case Report: The two patients were female with a long medical history of proctologic disease such as anal fistula, anal prolapse, hemorrhoids and bleeding. Patient one: a 71 year old woman. She presented with, bulging mass in the anal canal. The biopsies concluded to a medially differentiated adenocarcinoma. The patient did not show up for a year due to personal reasons. The patient got a flash radiation followed by Abdomino perineal resection (APR). The anatomopathology concluded to a mucinous adenocarcinoma. The patient died within a month after surgery due to a deteriorated heart condition. Patient2: A 62 year old female patient. She presented in april 2007 with a 4 cm mobile, bulging mass mass in the anal canal with 3 anal fistula. The patient had neoadjuvant chemoradiation followed by an APR. The hitology concluded to a mucinous adenocarcinoma of the anal glands. The follow up of the patient until 08/09/2015 showed no sign of recurrence. Conclusion: The diagnosis is often late, in an advanced stage of the sickness. Recurrent or non recurrent fistula-in-ano requires multiple biopsies for pathology analysis in order to screen a related cancer. Early suspicion is crucial to avoid delayed diagnosis and treatment .
Authors and Affiliations
Ghalleb M, Jaidane O, Boujelbene N, Rezguani M, Chemlali M, Benzarti Z, Dhieb T, Mrad K, Rahal K
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