Primary squamous cell carcinoma of breast: A Rare Case Report
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2017, Vol 3, Issue 2
Abstract
Primary squamous cell carcinoma (SCC) of breast is a pure epithelial type of metaplastic carcinoma accounting for less than 0.1% of all breast cancers. A 70 year female presented with left breast lump of 4 months duration. Toilet mastectomy was done. Histopathology proved it to be primary SCC (large cell keratinizing) of breast. On immunohistochemistry, tumor cells were positive for pancytokeratin and epidermal growth factor receptor and negative for estrogen, progesterone receptors and HER-2/neu (triple negative). On follow up, after 1 month, patient presented with recurrence and metastasis to ipsilateral axillary lymph nodes. This case is presented for its rarity.
Authors and Affiliations
Rekha M. Haravi, Bhumika J. Bhandari, Shreekant K. Kittur, Sabu N. Satihal
Keywords
Related Articles
- EP ID EP263923
- DOI 10.17511/jopm.2017.i2.07
- Views 138
- Downloads 0
Two cases of spindle cell carcinoma with a histopathological review of biphasic tumours of head and neck
Spindle cell carcinoma (SPCC) is a very rare and unique biphasic variant of squamous cell carcinoma (SCC) which is a very rare malignancy of head and neck region.Spindle cell tumours are challenging feature of head and n...
Pancytopenia: A multidisciplinary assessment of hemato-etiological and clinical spectrum in a tertiary care hospital
Background: The causes of pancytopenia range from simple, completely treatable diseases to serious life-threatening conditions. A thorough evaluation of these cases is mandatory as it would benefit the patients to receiv...
Clinico-histopathological analysis of malignant soft tissue tumors
Background: Aim of the study was to analyze the histopathological findings in various malignant soft tissue tumors and to study its incidence in relation to age, gender and anatomical site. Material and Method: Total of...
Cell blocks prepared from gynaecologic liquid based specimens: as a source for further ancillary techniques
Background: Cervical cancer is the second most common cancer among women worldwide and leading causes of cancer deaths amongst women. Cell blocks prepared from liquid-based specimens can serve as a useful adjunct and cel...
A Retrospective study of 130 cases in all age group presented with palpable head and neck swelling
Introduction: FNAC is a simple, quick, inexpensive and minimally invasive technique for early diagnosis of palpable lesions in Head and neck. It is usually performed in outpatient department with nearly no complications....