Profile of Infective Endocarditis in Nigerian Children
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 22, Issue 8
Abstract
Background: Infective endocarditis (IE) was initially thought to be uncommon in children but is on the increase due to improved cardiac services in the developing world. Aims: Aims of this study is to describe the profile of IE in children in Jos, Nigeria and identify the peculiarities of the disease in the locality. Methods: Case records of children diagnosed with IE based on the modified Duke’s criteria over a seven year period were retrospectively reviewed in a tertiary hospital. Their clinical manifestations, blood culture isolates, presence or absence of vegetations and clinical outcomes were documented and analyzed using Epi Info 7. Results: Case records of thirty children were reviewed. The number of children managed increased yearly with 10 (33.3%) of them seen in the last year of the study. The clinical features were mainly non-specific - fever (70.0%), congestive cardiac failure (63.3%) and anorexia (63.3%) being the major findings. Staphylococcus aureus was the commonest isolate, present in 5 (45.5%) of the 11 blood culture-positive cases. Other organisms isolated were Klebsiella species in 3 (27.3%), Pseudomonas aeruginosa in 2 (18.2%) and Acinetobacter baumami in 1 (9.1%) child. Vegetations were detected in 12 (40.0%) children, most of them located on the mitral valve. Mortality occurred in 8 (26.7%) children and was significantly higher in males – P = 0.02. Conclusion: There is a marked increase in the number of children admitted and managed for IE in the last year of the study possibly due to an increased index of clinical suspicion of IE. A high index of suspicion is required for diagnosis because many children presented with nonspecific clinical features.
Authors and Affiliations
O. O. Ige, C. S. Yilgwan, U. Diala, H. O. Akhiwu, F. Baba, M. Bok
Keywords
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- EP ID EP311919
- DOI 10.9734/JAMMR/2017/34955
- Views 36
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