PROGNOSIS OF BIOLOGICAL ACTIVITY AND DRUG-LIKE COMPLEX OF THE RANUNCULACEAE FAMILY AS A SEARCH FOR NEW EFFECTIVE ACTIVE SUBSTANCES
Journal Title: Вчені записки Таврійського національного університету імені В. І. Вернадського. Серія: Технічні науки - Year 2018, Vol 29, Issue 6
Abstract
Despite the huge arsenal of available drugs, the problem of finding new high-performance medicines remains relevant. Therefore, nowadays increasingly the initial stage of the search for pharmacologically active substances is becoming the use of experimental methods in silico. The article investigates the effectiveness of some biologically active substances of the family Ranunculaceae. A virtual screening was conducted that showed the prospects of used biologically active substances for further use in pharmacy and medicine. With the help of prognostication programs, biological activity, main and secondary pharmacological effects, mechanisms of action, carcinogenicity, and others have been obtained. The expediency of further investigation of selected biologically active substances has been established.
Authors and Affiliations
Ю. І. Колб, Р. Т. Конечна, В. П. Новіков
Keywords
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