PROGNOSTIC FACTORS OF ACUTE ISCHEMIC STROKE IN POSTERIOR CIRCULATION FOR ASSESSMENT OF ITS CLINICAL COURSE AND OUTCOMES
Journal Title: Ukrainian Scientific Medical Youth Journal / Український Науково-Медичний Молодіжний Журнал - Year 2013, Vol 73, Issue 2
Abstract
Knowledge of clinical peculiarities of the course of ischemic strokes in posterior circulation (PC), early identification of unfavorable outcome factors will improve the results of treatment of ischemic strokes and to predict clinical consequences. 145 patients were involved in the study with acute PC cerebral infarction. All patients were hospitalized during the first 6-24 hours after the appearance of the primary symptoms of a stroke. According to the recovery degree of neurological functions, using the modified Rankin scale at 21 days of treatment, all patients were divided into two groups: 1-st group (53 patients) had unfavorable functional outcome (3-6 points) and the 2-nd group (92 patients) – favorable (0-2 points). Demographic baselines, risk factors for ischemic stroke, basic neurological deficit and dynamics of its recovery, the results of laboratory tests were analyzed in both groups in details. Significant improvement of neurological deficits in patients of the 1-st group was recorded on the 14-th day of observation with the help of NIHSS and B. Hoffenberth et al. scales, while among patients in the 2-nd group – already on the 7-th day. The factors, affecting the unfavourable functional outcome of patients with ischemic stroke in PC on the 21-st day of observation, were determined. A statistically significant difference of indicators in both groups were found for such factors as: the severity of the neurological deficits by NIHSS and B. Hoffenberth et al. scores (p<0.001), the degree of consciousness by Glasgow coma scale (p <0.001), presence of atrial fibrillation (p = 0.03), cardioembolic stroke subtype (p = 0.004), the presence of transient ischemic attacks in anamnesis (p=0, 02), the combined lesion of different PC structures (p<0.001).
Authors and Affiliations
K. V. Antonenko, L. I. Sokolova
Keywords
Related Articles
- EP ID EP94923
- DOI -
- Views 80
- Downloads 0
STATE OF LOCAL IMMUNITY IN CHILDREN WITH ALLERGIC PREDISPOSITION
Article is dedicated to coverage of state of local immunity of the children with allergic predisposition for prophylaxis of it transformation in a disease.
E-HEALTH IMPLEMENTATION – READINESS OF BULGARIAN OPHTHALMOLOGISTS
The results from the survey suggest that while a large part of ophthalmologists are at least partly prepared, there still are a lot of ophthalmologists who are unconvinced of the benefits of e-health. Additional informat...
STRUCTURAL DISTURBANCES IN BRAIN CORTEX AT EXPERIMENTAL STROKE PHARMACOTHERAPY
In experimental study we showed the development of the structural changes in rat cerebral cortex during the second stroke. In the acute phase of stroke we observed edema of neurons and destruction of synapses in cerebral...
PUBLIC ASSOCIATIONS OF DERMATOVENEREOLOGISTS IN UKRAINE.ON THE WAY FROM SCIENTIFIC SOCIETIES TO MEDICAL SELF-GOVERNMENT
The article describes the main stages of the integration processes in the Ukrainian dermatovenereology, reflecting the formation of a professional association of Dermatovenereologists and Cosmetologists, as well as prosp...
POLYMORPHISM OF TNF-ALPHA GENE IN LOCALIZED AND GENERALIZED PYOSEPTIC DISEASES IN CHILDREN
In the article is shown the data on single polymorphism of a TNF-ALPHA gene as a predictor of the development of pyoseptic children diseases generalized forms. 27 children with localized and generalized pyoseptic disease...