Prognostic Factors on Survival of Rasoul-e-Akram Hospital Patients with Colorectal Cancer: A Survival Analysis
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 5
Abstract
ABSTRACT Introduction: Colorectal Cancer (CRC) also called colon cancer or intestine cancer is characterised by cancerous growth of cells in the rectum, colon and appendix. CRC is the fourth most common form of cancer after skin, gastric, bladder and prostate cancers among Iranian population, since 6-8 people per 10,000 people suffer from this disease. Aim: To evaluate the prognostic factors on survival of patients with CRC, in Rasool-e-Akram Hospital in Tehran, Iran. Materials and Methods: The population under study included patients with CRC, admitted between 30 March 2010 to 29 March 2013, in Rasoul-e-Akram teaching hospital affiliated with Iran University of Medical Sciences, Tehran, Iran. The event was death from CRC and any other cause. Possible prognostic variables were selected from documents. A multivariate Cox regression model was performed to study the concurrent effect of parameters on survival after taking into account the parallel effect of residual factors. Results: In this research 80 patients were studied. With respect to inclusion and exclusion criteria 68 patients were enrolled and data related to 68 patients were exposed to statistical analysis. Median and mean age of patients were equal to 55.5 and 55.0 years, respectively with standard deviation of 13.9 years. Only “Logarithm of White Blood Cell” showed a significant effect on survival of patients with CRC. Conclusion: The results of our study showed the effect of WBC on survival of patients with CRC. Accordingly the increased one unit of log WBC increased the death hazard by 21.22 times in CRC patient.
Authors and Affiliations
Shahram Agah, Elham Vafaei, Abolfazl Akbari, Mansoureh Tavousi, Mojtaba Soltani-Kermanshahi
Keywords
Related Articles
- EP ID EP584525
- DOI 10.7860/JCDR/2019/40924.12883
- Views 92
- Downloads 0
Is Low Cholesterol a Predisposing Factor for Primary Intracerebral Haemorrhage? A South Indian Perspective
ABSTRACT Introduction: Stroke is an important cause of mortality and morbidity in low-income and middle-income countries like India. Primary Intracerebral Haemorrhage (PICH) refers to Intracerebral Haemorrhage (ICH) in t...
Bilateral Primary Papillary Serous Carcinoma of the Fallopian Tube
Primary fallopian tube carcinoma is considered one of the rarest female genital cancers, and its bilateral occurrence is even rarer. Because of the rarity of fallopian tube carcinomas as well as the clinical presentation...
Carcinosarcoma Gallbladder: A Rare Variety of Gallbladder Malignancy
ABSTRACT Gallbladder malignancy is frequently found in Indian population. Most of them are adenocarcinoma variety whereas carcinosarcoma variety is quite rare. It is typically characterised by presence of both epithelial...
Regulation of Molecular Diagnostic (NAT) Kits For HBV, HCV and HIV in India
Letter to Editor
Variation in the Duration of Recumbency Post-spinal Anaesthesia in Relation to the Occurrence of Post-dural Puncture Headache
ABSTRACT Introduction: Post-Dural Puncture Headache (PDPH) remains one of the most dreaded complications of spinal anaesthesia. Duration of recumbency has been considered as a factor in the occurrence of PDPH. Aim: Thi...